Mannosyl-3-phosphoglycerate phosphatase

From Wikipedia, the free encyclopedia

In enzymology, a mannosyl-3-phosphoglycerate phosphatase (EC 3.1.3.70) is an enzyme that catalyzes the chemical reaction

2(alpha-D-mannosyl)-3-phosphoglycerate + H₂O 2(alpha-D-mannosyl)-D-glycerate + phosphate

Thus, the two substrates of this enzyme are 2(alpha-D-mannosyl)-3-phosphoglycerate and H₂O, whereas its two products are 2(alpha-D-mannosyl)-D-glycerate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is alpha-D-mannosyl-3-phosphoglycerate phosphohydrolase.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1WZC and 1XVI.

[edit] References

• IUBMB entry for 3.1.3.70
• BRENDA references for 3.1.3.70 (Recommended.)
• PubMed references for 3.1.3.70
• PubMed Central references for 3.1.3.70
• Google Scholar references for 3.1.3.70
• Empadinhas N, Marugg JD, Borges N, Santos H, da Costa MS (2001). "Pathway for the synthesis of mannosylglycerate in the hyperthermophilic archaeon Pyrococcus horikoshii. Biochemical and genetic characterization of key enzymes". J. Biol. Chem. 276: 43580–8. doi:10.1074/jbc.M108054200. PMID 11562374. 

[edit] External links

• IUBMB entry for 3.1.3.70

• KEGG entry for 3.1.3.70

• BRENDA entry for 3.1.3.70

• NiceZyme view of 3.1.3.70

• EC2PDB: PDB structures for 3.1.3.70

• PRIAM entry for 3.1.3.70

• PUMA2 entry for 3.1.3.70

• IntEnz: Integrated Enzyme entry for 3.1.3.70

• MetaCyc entry for 3.1.3.70

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050531: mannosyl-3-phosphoglycerate phosphatase

• AMIGO entry for GO code 0050531: mannosyl-3-phosphoglycerate phosphatase