Maltose-transporting ATPase

From Wikipedia, the free encyclopedia

In enzymology, a maltose-transporting ATPase (EC 3.6.3.19) is an enzyme that catalyzes the chemical reaction

ATP + H₂O + maltoseout $\rightleftharpoons$ ADP + phosphate + maltosein

The 3 substrates of this enzyme are ATP, H₂O, and maltose, whereas its 3 products are ADP, phosphate, and maltose.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (maltose-importing). This enzyme participates in abc transporters - general.

1 Structural studies
2 References
3 External links
- 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2AWN and 2AWO.

[edit] References

IUBMB entry for 3.6.3.19
BRENDA references for 3.6.3.19 (Recommended.)
PubMed references for 3.6.3.19
PubMed Central references for 3.6.3.19
Google Scholar references for 3.6.3.19
Higgins CF (1992). "ABC transporters: from microorganisms to man". Annu. Rev. Cell. Biol. 8: 67–113. doi:10.1146/annurev.cb.08.110192.000435. PMID 1282354.
Dassa E, Muir S (1993). "Membrane topology of MalG, an inner membrane protein from the maltose transport system of Escherichia coli". Mol. Microbiol. 7: 29–38. doi:10.1111/j.1365-2958.1993.tb01094.x. PMID 8437518.
Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH Jr (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases". Res. Microbiol. 146: 271–8. PMID 7569321.
Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. 40: 81–136. PMID 9889977.
Griffiths JK and Sansom CE. "The Transporter Factsbook, Academic Press, San Diego, 1998".