Maltose-6'-phosphate glucosidase

From Wikipedia, the free encyclopedia

In enzymology, a maltose-6'-phosphate glucosidase (EC 3.2.1.122) is an enzyme that catalyzes the chemical reaction

maltose 6'-phosphate + H₂O $\rightleftharpoons$ D-glucose + D-glucose 6-phosphate

Thus, the two substrates of this enzyme are maltose 6'-phosphate and H₂O, whereas its two products are D-glucose and D-glucose 6-phosphate.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is maltose-6'-phosphate 6-phosphoglucohydrolase. This enzyme is also called phospho-alpha-glucosidase. This enzyme participates in starch and sucrose metabolism.

1 Structural studies
2 References
3 External links
- 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1U8X.

[edit] References

IUBMB entry for 3.2.1.122
BRENDA references for 3.2.1.122 (Recommended.)
PubMed references for 3.2.1.122
PubMed Central references for 3.2.1.122
Google Scholar references for 3.2.1.122
Thompson J, Gentry-Weeks CR, Nguyen NY, Folk JE, Robrish SA (1995). "Purification from Fusobacterium mortiferum ATCC 25557 of a 6-phosphoryl-O-alpha-D-glucopyranosyl:6-phosphoglucohydrolase that hydrolyzes maltose 6-phosphate and related phospho-alpha-D-glucosides". J. Bacteriol. 177: 2505–12. PMID 7730284.