Maleylpyruvate isomerase

From Wikipedia, the free encyclopedia

In enzymology, a maleylpyruvate isomerase (EC 5.2.1.4) is an enzyme that catalyzes the chemical reaction

3-maleylpyruvate 3-fumarylpyruvate

Hence, this enzyme has one substrate, 3-maleylpyruvate, and one product, 3-fumarylpyruvate.

This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is 3-maleylpyruvate cis-trans-isomerase. This enzyme participates in tyrosine metabolism.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2NSF and 2NSG.

[edit] References

• IUBMB entry for 5.2.1.4
• BRENDA references for 5.2.1.4 (Recommended.)
• PubMed references for 5.2.1.4
• PubMed Central references for 5.2.1.4
• Google Scholar references for 5.2.1.4
• Lack L (1961). "Enzymic cis-trans isomerization of maleylpyruvic acid". J. Biol. Chem. 236: 2835–2840. 

[edit] External links

The CAS registry number for this enzyme class is 9023-77-2.

• IUBMB entry for 5.2.1.4

• KEGG entry for 5.2.1.4

• BRENDA entry for 5.2.1.4

• NiceZyme view of 5.2.1.4

• EC2PDB: PDB structures for 5.2.1.4

• PRIAM entry for 5.2.1.4

• PUMA2 entry for 5.2.1.4

• IntEnz: Integrated Enzyme entry for 5.2.1.4

• MetaCyc entry for 5.2.1.4

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050077: maleylpyruvate isomerase

• AMIGO entry for GO code 0050077: maleylpyruvate isomerase