Maleylacetate reductase

From Wikipedia, the free encyclopedia

In enzymology, a maleylacetate reductase (EC 1.3.1.32) is an enzyme that catalyzes the chemical reaction

3-oxoadipate + NAD(P)+ 2-maleylacetate + NAD(P)H + H⁺

The 3 substrates of this enzyme are 3-oxoadipate, NAD⁺, and NADP⁺, whereas its 4 products are 2-maleylacetate, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-oxoadipate:NAD(P)+ oxidoreductase. This enzyme is also called maleolylacetate reductase. This enzyme participates in 3 metabolic pathways: gamma-hexachlorocyclohexane degradation, benzoate degradation via hydroxylation, and 1,4-dichlorobenzene degradation.

[edit] References

• IUBMB entry for 1.3.1.32
• BRENDA references for 1.3.1.32 (Recommended.)
• PubMed references for 1.3.1.32
• PubMed Central references for 1.3.1.32
• Google Scholar references for 1.3.1.32
• Gaal AB, Neujahr HY (1980). "Maleylacetate reductase from Trichosporon cutaneum". Biochem. J. 185: 783–6. PMID 7387635. 
• Gaal AB and Neujahr HY (1981). "Induction of phenol-metabolizing enzymes in Trichosporon cutaneum". Arch. Microbiol. 130: 54–58. 

[edit] External links

The CAS registry number for this enzyme class is 69669-65-4.

• IUBMB entry for 1.3.1.32

• KEGG entry for 1.3.1.32

• BRENDA entry for 1.3.1.32

• NiceZyme view of 1.3.1.32

• EC2PDB: PDB structures for 1.3.1.32

• PRIAM entry for 1.3.1.32

• PUMA2 entry for 1.3.1.32

• IntEnz: Integrated Enzyme entry for 1.3.1.32

• MetaCyc entry for 1.3.1.32

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018506: maleylacetate reductase

• AMIGO entry for GO code 0018506: maleylacetate reductase