Maleimide hydrolase

From Wikipedia, the free encyclopedia

In enzymology, a maleimide hydrolase (EC 3.5.2.16) is an enzyme that catalyzes the chemical reaction

maleimide + H₂O maleamic acid

Thus, the two substrates of this enzyme are maleimide and H₂O, whereas its product is maleamic acid.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. The systematic name of this enzyme class is cyclic-imide amidohydrolase (decyclizing). Other names in common use include imidase, cyclic imide hydrolase, and cyclic-imide amidohydrolase (decyclicizing) [misprint].

[edit] References

• IUBMB entry for 3.5.2.16
• BRENDA references for 3.5.2.16 (Recommended.)
• PubMed references for 3.5.2.16
• PubMed Central references for 3.5.2.16
• Google Scholar references for 3.5.2.16
• Ogawa J, Soong CL, Honda M, Shimizu S (1997). "Imidase, a dihydropyrimidinase-like enzyme involved in the metabolism of cyclic imides". Eur. J. Biochem. 243: 322–7. doi:10.1111/j.1432-1033.1997.0322a.x. PMID 9030755. 

[edit] External links

• IUBMB entry for 3.5.2.16

• KEGG entry for 3.5.2.16

• BRENDA entry for 3.5.2.16

• NiceZyme view of 3.5.2.16

• EC2PDB: PDB structures for 3.5.2.16

• PRIAM entry for 3.5.2.16

• PUMA2 entry for 3.5.2.16

• IntEnz: Integrated Enzyme entry for 3.5.2.16

• MetaCyc entry for 3.5.2.16

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050539: maleimide hydrolase

• AMIGO entry for GO code 0050539: maleimide hydrolase