Maleate hydratase

From Wikipedia, the free encyclopedia

In enzymology, a maleate hydratase (EC 4.2.1.31) is an enzyme that catalyzes the chemical reaction

(R)-malate maleate + H₂O

Hence, this enzyme has one substrate, (R)-malate, and two products, maleate and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (R)-malate hydro-lyase (maleate-forming). Other names in common use include D-malate hydro-lyase, malease, and (R)-malate hydro-lyase. This enzyme participates in butanoate metabolism.

[edit] References

• IUBMB entry for 4.2.1.31
• BRENDA references for 4.2.1.31 (Recommended.)
• PubMed references for 4.2.1.31
• PubMed Central references for 4.2.1.31
• Google Scholar references for 4.2.1.31
• Britten JS, Morell H, Taggart JV (1969). "Anion activation of maleate hydratase". Biochim. Biophys. Acta. 185: 220–7. PMID 5796106. 
• SACKS W, JENSEN CO (1951). "Malease, a hydrase from corn kernels". J. Biol. Chem. 192: 231–6. PMID 14917669. 

[edit] External links

The CAS registry number for this enzyme class is 37290-71-4.

• IUBMB entry for 4.2.1.31

• KEGG entry for 4.2.1.31

• BRENDA entry for 4.2.1.31

• NiceZyme view of 4.2.1.31

• EC2PDB: PDB structures for 4.2.1.31

• PRIAM entry for 4.2.1.31

• PUMA2 entry for 4.2.1.31

• IntEnz: Integrated Enzyme entry for 4.2.1.31

• MetaCyc entry for 4.2.1.31

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050075: maleate hydratase

• AMIGO entry for GO code 0050075: maleate hydratase