Major facilitator family

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Major Facilitator Superfamily
Identifiers
Symbol	MFS_1
Pfam	PF07690
InterPro	IPR011701
PROSITE	PDOC50850
SCOP	1pw4
TCDB	2.A.1
OPM family	15
OPM protein	1pw4
Available PDB structures: 1pw4A:34-400

The Major Facilitator Superfamily (MFS) transporters are secondary carriers transporting small solutes in response to chemiosmotic ion gradients^[1]^[2].

[edit] Human proteins containing this domain

FLVCR; FLVCR1; FLVCR2;
HIAT1; HIATL1; HMFN2567;
MFSD1; MFSD2; MFSD3; MFSD4; MFSD7; MFSD8; MFSD9;
NAGLT1;
OAT1;
OAT1-4; OAT7; OCTN2VT;
SLC16A1; SLC16A10; SLC16A11; SLC16A12; SLC16A13; SLC16A14; SLC16A2; SLC16A3; SLC16A4; SLC16A5; SLC16A6; SLC16A7; SLC16A8; SLC16A9; SLC17A1; SLC17A2; SLC17A3; SLC17A4; SLC17A5; SLC17A6; SLC17A7; SLC17A8; SLC18A1; SLC18A2; SLC18A3; SLC22A1; SLC22A10; SLC22A11; SLC22A12; SLC22A14; SLC22A15; SLC22A16; SLC22A17; SLC22A18; SLC22A2; SLC22A20; SLC22A3; SLC22A5; SLC22A6; SLC22A7; SLC22A8; SLC22A9; SLC2A13; SLC2A5; SLC37A1; SLC37A2; SLC37A3; SLC37A4; SLC43A2; SLC43A3; SLC45A1; SLC45A3; SLC46A1; SLC46A3;
SPIN1; SPNS1; SPNS2; SPNS3;
SV2A; SV2B; SV2C; SVOP; SVOPL; *TETRAN; TSCOT;
hCT2; hOAT1; hOCT1; hROAT1;

[edit] References

^ Paulsen IT, Pao SS, Saier Jr MH (1998). "Major facilitator superfamily". Microbiol. Mol. Biol. Rev. 62 (1): 1–34. PMID 9529885.
^ Gould GW, Walmsley AR, Barrett MP, Bringaud F (1998). "Sugar transporters from bacteria, parasites and mammals: structure-activity relationships". Trends Biochem. Sci. 23 (12): 476–481. doi:10.1016/S0968-0004(98)01326-7. PMID 9868370.