Mae-Wan Ho

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Mae-Wan Ho (b. 12 November 1941, Hong Kong) is a reader in genetics and biophysics at the Open University in the United Kingdom.[1] who is known for her critical views on genetic modification.[2] Ho has authored or co-authored a number of publications, including 10 books, such as The Rainbow and the Worm, the Physics of Organisms (1993, 1998), Genetic Engineering Dream or Nightmare? (1998, 1999), and Living with the Fluid Genome (2003). Ho is the director of the The Institute of Science in Society, an interest group that campaigns against the use of biotechnology.[3]

Ho has expressed concerns about the spread of altered genes through horizontal gene transfer and that the experimental alteration of genetic structures may be out of control. One of her concerns is that the antibiotic resistant gene that was isolated from bacteria and used in some GM crops might cross back from plants by horizontal gene transfer to different species of bacteria, because "If this happened it would leave us unable to treat major illnesses like meningitis and E coli."[4] Her views were published in an opinion article based on a review of others' research.[5] The arguments and conclusions of this article were heavily criticized by prominent plant scientists,[6] and the claims of the article criticized in detail in a response that was published in the same journal.[7] A review on the topic published in 2008 in the Annual Review of Plant Biology stated that "These speculations have been extensively rebutted by the scientific community".[8]

Ho, together with Joe Cummins of the University of Western Ontario, has argued that a sterility gene engineered into a crop could be transferred to other crops or wild relatives and that "This could severely compromise the agronomic performance of conventional crops and cause wild relatives to go extinct". They argued that this process could also produce genetic instabilities, which might be "leading to catastrophic breakdown", and concluded that there are no data to assure that this has not happened or cannot happen.[9]

[edit] Bibliography

  • Mae-Wan Ho. The rainbow and the worm, the physics of organisms, Singapore; River Edge, NJ: World Scientific, 1998. ISBN 981024813X.
  • Mae-Wan Ho. Genetic engineering: dream or nightmare? Turning the tide on the brave new world of bad science and big business, New York, NY: Continuum, 2000. ISBN 0826412572.
  • Mae-Wan Ho. Living with the fluid genome, London, UK: Institute of Science in Society; Penang, Malaysia: Third World Network, 2003. ISBN 0954492307.
  • Mae-Wan Ho, Sam Burcher, Rhea Gala and Vejko Velkovic. Unraveling AIDS: the independent science and promising alternative therapies, Ridgefield, CT: Vital Health Pub., 2005. ISBN 1890612472.

[edit] References

  1. ^ Polly Curtis, "Exploitation on the agenda at ethics forum", The Guardian, February 22, 2002. Reprint. Accessed 2008-06-09.
  2. ^ Tim Gardam, Director of programmes, Channel 4, "Seeds of discontent at C4", The Guardian, March 18 2000. Reprint. Accessed 2008-06-09.
  3. ^ ISIS Report 2000
  4. ^ Antony Barnett, "GM genes 'jump species barrier', GM food: special report", The Guardian, May 28 2000. Reprint. Accessed 2008-06-09.
  5. ^ Ho, M.W.; Ryan, A.; Cummins, J. (1999). "Cauliflower Mosaic Viral Promoter-A Recipe for Disaster?". Microbial Ecology in Health and Disease 11 (4): 194-197. 
  6. ^ Scientists avert new GMO crisis - Nature Biotechnology. Nature (journal). Retrieved on 2008-06-10.
  7. ^ Hull, R.; Covey, S.N.; Dale, P. (2000). "Genetically modified plants and the 35S promoter: assessing the risks and enhancing the debate". Microbial Ecology in Health and Disease 12 (1): 1-5. 
  8. ^ Lemaux PG (2008). "Genetically Engineered Plants and Foods: A Scientist's Analysis of the Issues (Part I)". Annu Rev Plant Biol 59: 771–812. doi:10.1146/annurev.arplant.58.032806.103840. PMID 18284373. 
  9. ^ Donald MacLeod, "Who's listening? Will public opinion on genetically modified crops make any difference to the government?", The Guardian, May 19 2003. Reprint. Accessed 2008-06-09.

[edit] External links