Lysine N-acetyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a lysine N-acetyltransferase (EC 2.3.1.32) is an enzyme that catalyzes the chemical reaction

acetyl phosphate + L-lysine phosphate + N₆-acetyl-L-lysine

Thus, the two substrates of this enzyme are acetyl phosphate and L-lysine, whereas its two products are phosphate and N6-acetyl-L-lysine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-phosphate:L-lysine N6-acetyltransferase. Other names in common use include lysine acetyltransferase, and acetyl-phosphate:L-lysine 6-N-acetyltransferase. This enzyme participates in lysine degradation.

[edit] References

• IUBMB entry for 2.3.1.32
• BRENDA references for 2.3.1.32 (Recommended.)
• PubMed references for 2.3.1.32
• PubMed Central references for 2.3.1.32
• Google Scholar references for 2.3.1.32
• PAIK WK, KIM S (1964). "ENZYMIC SYNTHESIS OF EPSILON-N-ACETYL-L-LYSINE". Arch. Biochem. Biophys. 108: 221–9. PMID 14240571. 

[edit] External links

The CAS registry number for this enzyme class is 37257-12-8.

• IUBMB entry for 2.3.1.32

• KEGG entry for 2.3.1.32

• BRENDA entry for 2.3.1.32

• NiceZyme view of 2.3.1.32

• EC2PDB: PDB structures for 2.3.1.32

• PRIAM entry for 2.3.1.32

• PUMA2 entry for 2.3.1.32

• IntEnz: Integrated Enzyme entry for 2.3.1.32

• MetaCyc entry for 2.3.1.32

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0004468: lysine N-acetyltransferase

• AMIGO entry for GO code 0004468: lysine N-acetyltransferase