Lysine-pyruvate 6-transaminase

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In enzymology, a lysine-pyruvate 6-transaminase (EC 2.6.1.71) is an enzyme that catalyzes the chemical reaction

L-lysine + pyruvate L-2-aminoadipate 6-semialdehyde + L-alanine

Thus, the two substrates of this enzyme are L-lysine and pyruvate, whereas its two products are L-2-aminoadipate 6-semialdehyde and L-alanine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-lysine:pyruvate aminotransferase. Other names in common use include lysine-pyruvate aminotransferase, and Lys-AT.

[edit] References

• IUBMB entry for 2.6.1.71
• BRENDA references for 2.6.1.71 (Recommended.)
• PubMed references for 2.6.1.71
• PubMed Central references for 2.6.1.71
• Google Scholar references for 2.6.1.71
• Schmidt H, Bode R and Birnbaum D (1988). "A novel enzyme, L-lysine : pyruvate aminotransferase, catalyses the first step of lysine catabolism in Pichia guilliermondii". FEMS Microbiol. Lett. 49: 203–206. 

[edit] External links

The CAS registry number for this enzyme class is 114189-79-6.

• IUBMB entry for 2.6.1.71

• KEGG entry for 2.6.1.71

• BRENDA entry for 2.6.1.71

• NiceZyme view of 2.6.1.71

• EC2PDB: PDB structures for 2.6.1.71

• PRIAM entry for 2.6.1.71

• PUMA2 entry for 2.6.1.71

• IntEnz: Integrated Enzyme entry for 2.6.1.71

• MetaCyc entry for 2.6.1.71

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050065: lysine-pyruvate 6-transaminase

• AMIGO entry for GO code 0050065: lysine-pyruvate 6-transaminase