LY75
From Wikipedia, the free encyclopedia
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Lymphocyte antigen 75
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| Identifiers | ||||||||||||||
| Symbol(s) | LY75; CD205; CLEC13B; DEC-205; GP200-MR6 | |||||||||||||
| External IDs | OMIM: 604524 MGI: 106662 HomoloGene: 31085 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
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| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 4065 | 17076 | ||||||||||||
| Ensembl | ENSG00000054219 | ENSMUSG00000026980 | ||||||||||||
| Uniprot | O60449 | Q3UMG1 | ||||||||||||
| Refseq | NM_002349 (mRNA) NP_002340 (protein) |
NM_013825 (mRNA) NP_038853 (protein) |
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| Location | Chr 2: 160.37 - 160.47 Mb | Chr 2: 60.09 - 60.18 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Lymphocyte antigen 75, also known as LY75, is a human gene.[1]
LY75 has also recently been designated CD205 (cluster of differentiation 205).
[edit] References
[edit] Further reading
- Tungekar MF, Gatter KC, Ritter MA (1996). "Bladder carcinomas and normal urothelium universally express gp200-MR6, a molecule functionally associated with the interleukin 4 receptor (CD 124).". Br. J. Cancer 73 (4): 429–32. PMID 8595155.
- al-Tubuly AA, Luqmani YA, Shousha S, et al. (1996). "Differential expression of gp200-MR6 molecule in benign hyperplasia and down-regulation in invasive carcinoma of the breast.". Br. J. Cancer 74 (7): 1005–11. PMID 8855966.
- Kato M, Neil TK, Clark GJ, et al. (1998). "cDNA cloning of human DEC-205, a putative antigen-uptake receptor on dendritic cells.". Immunogenetics 47 (6): 442–50. PMID 9553150.
- McKay PF, Imami N, Johns M, et al. (1999). "The gp200-MR6 molecule which is functionally associated with the IL-4 receptor modulates B cell phenotype and is a novel member of the human macrophage mannose receptor family.". Eur. J. Immunol. 28 (12): 4071–83. PMID 9862343.
- Palmer DB, Crompton T, Marandi MB, et al. (1999). "Intrathymic function of the human cortical epithelial cell surface antigen gp200-MR6: single-chain antibodies to evolutionarily conserved determinants disrupt mouse thymus development.". Immunology 96 (2): 236–45. PMID 10233701.
- Guo M, Gong S, Maric S, et al. (2000). "A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells.". Hum. Immunol. 61 (8): 729–38. PMID 10980384.
- Kato M, Neil TK, Fearnley DB, et al. (2000). "Expression of multilectin receptors and comparative FITC-dextran uptake by human dendritic cells.". Int. Immunol. 12 (11): 1511–9. PMID 11058570.
- Kato M, Khan S, Gonzalez N, et al. (2003). "Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor DEC-205 (CD205) and a novel C-type lectin receptor DCL-1.". J. Biol. Chem. 278 (36): 34035–41. doi:. PMID 12824192.
- Bozzacco L, Trumpfheller C, Siegal FP, et al. (2007). "DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes.". Proc. Natl. Acad. Sci. U.S.A. 104 (4): 1289–94. doi:. PMID 17229838.
- Nonaka D, Henley JD, Chiriboga L, Yee H (2007). "Diagnostic utility of thymic epithelial markers CD205 (DEC205) and Foxn1 in thymic epithelial neoplasms.". Am. J. Surg. Pathol. 31 (7): 1038–44. doi:. PMID 17592270.
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