LY6E

From Wikipedia, the free encyclopedia

Lymphocyte antigen 6 complex, locus E

Identifiers

LY6E; RIG-E; RIGE; SCA-2; SCA2; TSA-1

External IDs

OMIM: 601384 MGI: 106651 HomoloGene: 56411

Gene ontology
Molecular Function:	• GPI anchor binding
Cellular Component:	• integral to plasma membrane • membrane
Biological Process:	• defense response • cell surface receptor linked signal transduction

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_002346 (mRNA)
NP_002337 (protein)

NM_008529 (mRNA)
NP_032555 (protein)

Location

Chr 8: 144.17 - 144.18 Mb

Chr 15: 74.78 - 74.79 Mb

Pubmed search

[1]

[2]

Lymphocyte antigen 6 complex, locus E, also known as LY6E, is a human gene.^[1]

[edit] References

^ Entrez Gene: LY6E lymphocyte antigen 6 complex, locus E.

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Mao M, Yu M, Tong JH, et al. (1996). "RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell.". Proc. Natl. Acad. Sci. U.S.A. 93 (12): 5910–4. PMID 8650192.
Capone MC, Gorman DM, Ching EP, Zlotnik A (1996). "Identification through bioinformatics of cDNAs encoding human thymic shared Ag-1/stem cell Ag-2. A new member of the human Ly-6 family.". J. Immunol. 157 (3): 969–73. PMID 8757598.
Brakenhoff RH, van Dijk M, Rood-Knippels EM, Snow GB (1997). "A gain of novel tissue specificity in the human Ly-6 gene E48.". J. Immunol. 159 (10): 4879–86. PMID 9366413.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Shan X, Bourdeau A, Rhoton A, et al. (1998). "Characterization and mapping to human chromosome 8q24.3 of Ly-6-related gene 9804 encoding an apparent homologue of mouse TSA-1.". J. Immunol. 160 (1): 197–208. PMID 9551972.
Kosugi A, Saitoh S, Noda S, et al. (1998). "Physical and functional association between thymic shared antigen-1/stem cell antigen-2 and the T cell receptor complex.". J. Biol. Chem. 273 (20): 12301–6. PMID 9575182.
Ding L, Shevach EM (2001). "Inhibition of the function of the FcgammaRIIB by a monoclonal antibody to thymic shared antigen-1, a Ly-6 family antigen.". Immunology 104 (1): 28–36. PMID 11576217.
Tulin EE, Onoda N, Nakata Y, et al. (2002). "SF20/IL-25, a novel bone marrow stroma-derived growth factor that binds to mouse thymic shared antigen-1 and supports lymphoid cell proliferation.". J. Immunol. 167 (11): 6338–47. PMID 11714798.
Zammit DJ, Berzins SP, Gill JW, et al. (2002). "Essential role for the lymphostromal plasma membrane Ly-6 superfamily molecule thymic shared antigen 1 in development of the embryonic adrenal gland.". Mol. Cell. Biol. 22 (3): 946–52. PMID 11784869.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
de Nooij-van Dalen AG, van Dongen GA, Smeets SJ, et al. (2003). "Characterization of the human Ly-6 antigens, the newly annotated member Ly-6K included, as molecular markers for head-and-neck squamous cell carcinoma.". Int. J. Cancer 103 (6): 768–74. doi:10.1002/ijc.10903. PMID 12516096.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.