Luteolin-7-O-glucuronide 2"-O-glucuronosyltransferase

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In enzymology, a luteolin-7-O-glucuronide 2"-O-glucuronosyltransferase (EC 2.4.1.190) is an enzyme that catalyzes the chemical reaction

UDP-glucuronate + luteolin 7-O-beta-D-glucuronide $\rightleftharpoons$ UDP + luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]

Thus, the two substrates of this enzyme are UDP-glucuronate and luteolin 7-O-beta-D-glucuronide, whereas its two products are UDP and [[luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]]].

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucuronate:luteolin-7-O-beta-D-glucuronide 2-O-glucuronosyltransferase. Other names in common use include uridine diphosphoglucuronate-luteolin 7-O-glucuronide, glucuronosyltransferase, LMT, and UDP-glucuronate:luteolin 7-O-glucuronide-glucuronosyltransferase.

[edit] References

IUBMB entry for 2.4.1.190
BRENDA references for 2.4.1.190 (Recommended.)
PubMed references for 2.4.1.190
PubMed Central references for 2.4.1.190
Google Scholar references for 2.4.1.190
Schulz M and Weissenbock G (1988). "3 specific UDP-glucuronate-flavone-glucuronosyl-transferases from primary leaves of Secale cereale". Phytochemistry 27: 1261–1267. doi:10.1016/0031-9422(88)80175-4.
Anhalt S and Weissenbock G (1992). "Subcellular localization of luteolin glucuronides and related enzymes in rye mesophyll". Planta 187: 83–88.