Lugduname

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Lugduname

IUPAC name	N-(4-Cyanophenyl)-N-(2,3-methylenedioxybenzyl)guanidinoacetic acid
Identifiers
CAS number	[180045-75-4]
SMILES	OC(CN/C(NC3=CC=C(C#N)C=C3)=N\CC1=CC=CC2=C1OCO2)=O
Properties
Molecular formula	C₁₈H₁₆N₄O₄
Molar mass	352.34 g mol^-1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Lugduname is the most potent sweetening agent known for humans. Lugduname has been estimated to be between 220,000 and 300,000 times as sweet as sucrose (table sugar), with estimates varying between studies. Lugduname is part of a family of extremely potent, guanidinocarboxylic acid, sweeteners with acetic acid functional groups on guanidine.

[edit] References

Jiong Chen, Mookda Pattarawarapan, Alex J. Zhang, and Kevin Burgess. Solution- and Solid-Phase Syntheses of Substituted Guanidinocarboxylic Acids. Journal of Combinatorial Chemistry. (2000) Vol. 2, No. 3 276

(Contains a synthetic method for Lugduname, see Scheme 2)

C. NOFRE, D. GLASER, J. -M. TINTI, and M. WANNER. Gustatory responses of pigs to sixty compounds tasting sweet to humans Journal of Animal Physiology and Animal Nutrition. 86 (2002), pp. 90-96