Talk:Low-density lipoprotein
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[edit] Minor issues
Under "lowering cholesterol" what is meant by the unfolding of carbohydrates to glucose. Isn't this language a little bit confusing. Does he mean the break down of carbohydrates. "unfolding is not a very good word. —Preceding unsigned comment added by Cag66 (talk • contribs) 05:49, 6 June 2008 (UTC)
I'm not even going to attempt to flesh this page out, since I'm not able to follow most of the links I can find on the subject, certainly not at the end of a work day (I'm a marine biologist damnit, not a doctor.. or whatever ;). However, if someone could kindly point out what the 'it' in the stub means that might help a bit (I kind of assume cholesterol, but not sure). Rgamble
I'm not sure how to convert the units to European ones (mmol/l) but I'm sure it needs to be done (the same goes for HDL and triglyceride). JFW | T@lk 19:52, 15 Apr 2004 (UTC)
This isn't my specialty, but according to google, it's Friedwald, not Freidwald. - ganaaaa 2-9-2006
[edit] Low carbohydrate diet
I removed the statement (written by an IP) that a low carbohydrate diet correlates with a healthy LDL distribution - there is no reference for it and it seems to be dubious. Icek 21:21, 30 March 2007 (UTC)
[edit] Ads
looks like this page may have just been flooded with ad placement. A cleanup/revert, if someone has time? Snellios 23:31, 10 June 2007 (UTC)
[edit] Citations
In the part (Recommended range; changing targets) I have added request for citation; there is mentioned scientific research in general instead of direct citation or reference and this creates false appearence that it has valid source. 213.215.88.108 16:28, 30 October 2007 (UTC)
[edit] Incomprehensible
This article is loaded with far too many technical terms and jargon to be easily understandable for the average reader. —Preceding unsigned comment added by 72.66.249.231 (talk) 17:06, 3 November 2007 (UTC)
- I agree that the dietary part is especially useless to the layman... maybe add some examples of food which would upregulate or downregulate LDL synthesis, or which foods may contain high levels of B3 (niacin). I also recall learning that moderate alcohol consumption may help regulate LDL (by means of HDL level regulation??). Might want to mention that too much alcohol would have the opposite effects, as metabolizing lots of EtOH would increase your triglyceride levels. —Preceding unsigned comment added by 137.122.149.212 (talk) 15:10, 7 November 2007 (UTC)
- Strongly Agree — The dietary portion presently reads: "Dietary Insulin induces HMG-CoA reductase activity, whereas glucagon downregulates it.[5] While glucagon production is stimulated by dietary protein ingestion, insulin production is stimulated by dietary carbohydrate. The rise of insulin is, in general, determined by the unfolding of carbohydrates into glucose during the process of digestion. Glucagon levels are very low when insulin levels are high." Upregulates? Downregulates? Unfolds? Does this just mean increase or decrease? I have a doctorate (not in medicine) and I still don't understand these four sentences. Will a medical person please put this in lay terms? And make some distinction between "dietary insulin" and what, injected insulin? -- LisaSmall T/C 11:26, 19 May 2008 (UTC)
[edit] Heterogeneity
PMID 6827999 - historical reference on the heterogeneity of LDL particles. JFW | T@lk 07:27, 16 March 2008 (UTC)
- Blame it on small dense LDL JFW | T@lk 07:28, 16 March 2008 (UTC)
