Loteprednol

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Loteprednol etabonate
Systematic (IUPAC) name
chloromethyl 17-ethoxycarbonyloxy- 11-hydroxy- 10,13-dimethyl-3-oxo- 7,8,9,11,12,14,15, 16-octahydro- 6H-cyclopenta[a] phenanthrene-17-carboxylate
Identifiers
CAS number 82034-46-6
ATC code S01BA14
PubChem 444025
DrugBank APRD01078
Chemical data
Formula C24H31ClO7 
Mol. mass 466.951 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

C(US)
Legal status

℞-only(US)
Routes  ?

Loteprednol (as the ester loteprednol etabonate) is a corticosteroid used in ophthalmology.

In the US, it is marketed by Bausch and Lomb as Lotemax.

Ocular applications for this drug include the treatment of chronic adenoviral keratitis, Thygeson’s keratitis, vernal keratoconjunctivitis, pingueculitis, and episcleritis. Its use has little or no effect on IOP

v • d • e
Corticosteroids - glucocorticoid/receptor and mineralocorticoid/receptor
(A07EA, C05AA, D07, D10AA, H02, R01AD, R03BA, S01BA, S02B, and S03B)
Endogenous
Others
Alclometasone, Amcinonide, Beclometasone, Betamethasone, Budesonide, Ciclesonide, Clobetasol, Clobetasone, Clocortolone, Cloprednol, Cortivazol, Deflazacort, Deoxycorticosterone, Desonide, Desoximetasone, Dexamethasone, Diflorasone, Diflucortolone, Difluprednate, Fluclorolone, Fludrocortisone, Fludroxycortide, Flumetasone, Flunisolide, Fluocinolone acetonide, Fluocinonide, Fluocortin, Fluocortolone, Fluorometholone, Fluperolone, Fluprednidene, Fluticasone, Formocortal, Halcinonide, Halometasone, Hydrocortisone aceponate, Hydrocortisone buteprate, Hydrocortisone butyrate, Loteprednol, Medrysone, Meprednisone, Methylprednisolone,Methylprednisolone aceponate, Mometasone furoate, Paramethasone, Prednicarbate, Prednisone, Prednisolone, Prednylidene, Rimexolone, Tixocortol, Triamcinolone, Ulobetasol
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