Lonafarnib
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| Lonafarnib | |
|---|---|
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| IUPAC name | 4-(2-(4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-yl)-1-piperidinyl)-2-oxoethyl)-1-piperidinecarboxamide |
| Identifiers | |
| CAS number | |
| PubChem | |
| SMILES | C1CN(CCC1CC(=O)N2CCC(CC2)C3C4=C (C=C(C=C4CCC5=CC(=CN=C35)Br)Cl)Br)C(=O)N |
| Properties | |
| Molecular formula | C27H31Br2ClN4O2 |
| Molar mass | 638.82164 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Lonafarnib is a farnesyltransferase inhibitor.[1]
[edit] References
- ^ Liu G, Marrinan CH, Taylor SA, et al (2007). "Enhancement of the antitumor activity of tamoxifen and anastrozole by the farnesyltransferase inhibitor lonafarnib (SCH66336)". Anticancer Drugs 18 (8): 923–31. doi:. PMID 17667598.
[edit] See also
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