Local gigantism

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Local gigantism affecting 2nd toe of a child
Local gigantism affecting 2nd toe of a child

Local gigantism or localised gigantism is a condition in which a certain part of the body acquires larger than normal size due to excessive growth of the anatomical structures or abnormal accumulation of substances. It is more common in fingers and toes, where it is termed macrodactyly. However, sometimes an entire limb may be enlarged.

Contents

[edit] Causes

Local gigantism may be caused by a heterogeneous group of both congenital and acquired conditions.

[edit] Congenital

An extreme example of local gigantism in Joseph Merrick, the Elephant Man, who had Proteus syndrome
An extreme example of local gigantism in Joseph Merrick, the Elephant Man, who had Proteus syndrome

Congenital causes include:

[edit] Acquired

There are a number of acquired causes of local gigantism. A body part can attain bigger size from causes as common as the following:

[edit] Treatment

As the causes of local gigantism are varied, treatment depends on the particular condition. Treatment may range from antibiotics and other medical therapy, to surgery in order to correct the anatomical anomaly.

[edit] References

  1. ^ Letter to the Indian Journal of Radiology and Imaging
  2. ^ Lassmann H, Gebhart W, Mamoli B, Niebauer G (1977). "Nervous lesions in a case of local gigantism". Acta Neuropathol. 38 (2): 109–15. PMID 878849. 
  3. ^ Chung IH, Kim NH, Choi IY (1973). "Macrodactylism associated with neurofibroma of the median nerve. A case report". Yonsei Med. J. 14: 49–52. PMID 4804132. 
  4. ^ Some case reports
  5. ^ Razzaghi A, Anastakis DJ (2005). "Lipofibromatous hamartoma: review of early diagnosis and treatment". Canadian Journal of Surgery. Journal canadien de chirurgie 48 (5): 394–9. PMID 16248139. 
  6. ^ Case report

[edit] External links