Talk:Lithium pharmacology

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I'm going to redirect the lithium salts page to here, since it was not really about lithium salts per se, but only their use as mood stabilizing drugs.

/+ i still think this is the best mood stabilizer, even though i was in intensive care for 2weeks after accidental overdose... it's extremely easy to die off of this if not taken properly, especially if it's in a time-released tablet... i don't know how it's done at other hospitals, but i was put on kidney dialysis to clear all the lithium from my blood... -- Lieutenant Colonel Frank Slade 02:01, 10 July 2006 (UTC)

/++ i'm not going to edit this page, but I'd have the first line say something like "The use of lithium salts to treat mania was first introduced by physicians of ancient Rome, when doctors recommended bathing in the springs in northern Italy which are abundant with the salts." ... I just have no citation but I've read it time and time again

Contents 1 Psychotropic effects 2 plasma concentrations 3 Citation 4 Lithium toxicity in overdose section 5 Kidney damage

[edit] Psychotropic effects

A previous editor changed the word "psychoactive" in the following sentence to "recreational":

"Unlike other psychoactive drugs, Li+ produces no obvious psychotropic effects, (such as euphoria) in normal individuals at therapeutic concentrations."

Lithium does not induce euphoria, hallucinations, or psychosis at therapeutic doses -- its undesired side-effects are almost completely negative in nature, something which is not true of most other psychoactive drugs. There's certainly no danger of lithium ever being misused as a recreational drug. -- The Anome 09:33, 27 October 2006 (UTC)

[edit] plasma concentrations

Hi, maybe to physicians is obvious but to average man I don't think so. It should be stated clear the "plasma concentrations" of lithium ion is referred only to the treatment period because normal level is about zero! Or well the less the better but surely less than 0.1 mmol Li+/litre. That is lithim ions are present in human body only in ultra traces because of absorption from compounds rarely found in food. Emilio 11:17, 21 April 2007 (UTC)

[edit] Citation

It is written in the article: "All of these were forced to remove lithium in 1948" but without any citation. I doubt that because it is also written that it was rediscovered in 1949 (by John Cade) after its effect was forgotten for many years. --134.155.99.42 18:52, 17 May 2007 (UTC)

[edit] Lithium toxicity in overdose section

"Lithium is, for the most part, completely incapable of being considered life threatening": this is bad grammar (something can't be "for the most part" as well as "completely"). It also contradicts the history section: "The rest of the world was slow to adopt this revolutionary treatment, largely because of deaths which resulted from even relatively minor overdosing".

[edit] Kidney damage

I took this drug from 2003 till 2007, had to stop because the Doctors found that my kidneys had been reduced in size. I am now on Depakote. 81.156.2.250 (talk) 11:02, 15 April 2008 (UTC)