LIMD1

From Wikipedia, the free encyclopedia

LIM domains containing 1

Identifiers

External IDs

OMIM: 604543 MGI: 1352502 HomoloGene: 8478

Gene ontology
Molecular Function:	• protein binding • zinc ion binding • metal ion binding
Biological Process:	• regulation of transcription, DNA-dependent • signal transduction • multicellular organismal development

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_014240 (mRNA)
NP_055055 (protein)

NM_013860 (mRNA)
NP_038888 (protein)

Location

Chr 3: 45.61 - 45.7 Mb

Chr 9: 123.33 - 123.37 Mb

Pubmed search

[1]

[2]

LIM domains containing 1, also known as LIMD1, is a human gene.^[1]

[edit] References

^ Entrez Gene: LIMD1 LIM domains containing 1.

[edit] Further reading

Kiss H, Kedra D, Yang Y, et al. (2000). "A novel gene containing LIM domains (LIMD1) is located within the common eliminated region 1 (C3CER1) in 3p21.3.". Hum. Genet. 105 (6): 552-9. PMID 10647888.
Jiang T, Altman S (2001). "Protein-protein interactions with subunits of human nuclear RNase P.". Proc. Natl. Acad. Sci. U.S.A. 98 (3): 920-5. doi:10.1073/pnas.021561498. PMID 11158571.
Kiss H, Kedra D, Kiss C, et al. (2001). "The LZTFL1 gene is a part of a transcriptional map covering 250 kb within the common eliminated region 1 (C3CER1) in 3p21.3.". Genomics 73 (1): 10-9. doi:10.1006/geno.2000.6498. PMID 11352561.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.". Anal. Chem. 76 (10): 2763-72. doi:10.1021/ac035352d. PMID 15144186.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324-32. doi:10.1101/gr.2334104. PMID 15231748.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Sharp TV, Munoz F, Bourboulia D, et al. (2004). "LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription.". Proc. Natl. Acad. Sci. U.S.A. 101 (47): 16531-6. doi:10.1073/pnas.0407123101. PMID 15542589.
Feng Y, Longmore GD (2005). "The LIM protein Ajuba influences interleukin-1-induced NF-kappaB activation by affecting the assembly and activity of the protein kinase Czeta/p62/TRAF6 signaling complex.". Mol. Cell. Biol. 25 (10): 4010-22. doi:10.1128/MCB.25.10.4010-4022.2005. PMID 15870274.
Huggins CJ, Gill M, Andrulis IL (2007). "Identification of rare variants in the hLIMD1 gene in breast cancer.". Cancer Genet. Cytogenet. 178 (1): 36-41. doi:10.1016/j.cancergencyto.2007.06.007. PMID 17889706.