Talk:Lidocaine

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I am a medical researcher, and am looking to find efficent ways to sterilize Lidocane. Anybody have some ideas??

Dissolve in water and filter-sterilize. If you need a solid again, then lyophilize. No offense, but if you really are a medical researcher, you should know this. ~K 17:51, 9 August 2005 (UTC)

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[edit] Side effects of Lidocaine

Shortly after receiving an injection of Lidocaine as a anesthetic to remove a splinter in my finger, I had a gout attack. I have been on Allopurinal for 15 years and have not had any attacks. Is this just coincidence or could there be any connection between the two?

My last gout attack happened after a dental procedure. However, I had NO anathesia. So, if there is a connection, I suspect it was the stress involved, and not the drugs. --Mdwyer 19:58, 30 November 2005 (UTC)
Please also remember that Wikipedia does not give medical advice. 65.95.235.43 22:17, 1 December 2005 (UTC)

[edit] Legality of Lidocaine

I believe the legality of lidocaine recently changed in the USA. I seem to remember that topical aloe vera with lidocaine burn treatments were once illegal, but have recently appeared in stores. Can someone make a comment about this? --Mdwyer 19:58, 30 November 2005 (UTC)

[edit] Side affects of Lidocaine

I was recently given an injection of lidocaine in my left knee, about 2 hrs later my right leg from the waist down is numb and tingly like it is asleep. Now 2 days later is also is affecting everything from the waist down except my left leg. I asked the doctor who gave me the shot and he said it in no way was related to the lidocaine, but I disagree. Any information would be helpful and appreciated. busdriverwithfour@msn.com

As another user has commented above, Wikipedia does not give medical advice. -60.227.33.74 07:33, 3 March 2006 (UTC)

Lidocaine is a fast-acting, fast-clearing local anesthetic. Very widely used. Anything COULD have ANY side effect! But it would be particularly odd for an injection to the left knee to have only after effects on the right leg. Systemic body-wide adverse effects such as allergy seem more likely. 69.87.194.172 18:41, 7 June 2006 (UTC)

This is an age-old question, usually to do with cars. They replace the fuel filter, and the next day the headlights won't work. It really really seems to the car's owner that, since the lights were perfectly fine until they were in the hands of those garage guys, there must be a connection. You were unlucky enough to have this numbness attack thingie happen while a doctor did something to another part of the body. Humans are naturally pattern-searching creatures. Gaviidae 13:41, 24 April 2007 (UTC)

[edit] Age-Dependent Half-Life

First off, apologies for my probable extreme ignorance of the subject. Recently undergoing toe surgery, I had to receive much more lidocaine than the normal dosage, as well as use a tourniquet to induce numbing. The lidocaine wore off after about 45 minutes. According to the doctor, the metabolism of young healthy males eats lidocaine like candy. Is the half life really that dependent on age/sex.health, or do I simply metabolize it faster than average? —Preceding unsigned comment added by Mr bowen2000 (talk • contribs)

That seems faster than normal... but then again, I usually use lidocaine with epinephrine which should help it last longer. Maybe no epinephrine was used? And maybe the surgery was in the upper jaw? Other than that, I do not have any ideas. - Dozenist talk 11:46, 20 December 2006 (UTC)
I was curious about the epinephrine myself, having noticed it listed on the label of the lidocaine ampoule at the dentist's office recently. Maybe this article, or the one on epinephrine, could explain more about this.--207.233.88.250 20:27, 15 February 2007 (UTC)

epinephrine (adrenaline) is used as a vasoconstrictor to counter the vasodilatory effects of lignocaine. This increases the duration of action as well as limits systemic toxicity since the drug is not circulating all around the body.

As an interesting side note, in the Netherlands, lidocaine is "lidocaine" when by itself until they add adrenaline. That's when it's called "xylocaine." for any of you foreign travellers out there : ) Procaine doesn't need the adrenaline added, since it's already a vasoconstrictor. Gaviidae 13:45, 24 April 2007 (UTC)

[edit] Melting Temperature

Lidocaine's melting point is listed as 154˚F. Is it necessary to melt it for administration? Perhaps it is in suspension? I get curious about all manner of esoterica. LorenzoB 07:00, 18 March 2007 (UTC)

[edit] U.S. schedule

I have looked and can't find the U.S. schedule for this...it's not in schedule lists that I could find. It is prescription, and that's all that I could verify. -Nathan J. Yoder 06:48, 24 March 2007 (UTC)

[edit] Lidocaine to delay male orgasm

Lidocaine is now commonly used as a spray or cream applied to the head of the penis a few minutes before coitus to desensitize the penis and therefore prolong pleasure for the woman. I've yet to see if it makes any difference myself, but supposedly if applied long enough before sex (or used with a condom) it doesn't desensitise the woman.

There are many products containing Lidocaine available on the market, eg. http://www.sexualconfidence.co.uk.

Benzocaine is used to the same purpose, for example in the Durex Performa condom.

[edit] Lidocaine and Cocaine

What's with the part about Lidocaine mixed with cocaine? I've never heard anything about that. If there is a reference, can someone post it? It sounds like someone is just trying to scare people out of using drugs. —Preceding unsigned comment added by Caribou1107 (talk • contribs) 01:39, 15 October 2007 (UTC)