LHFP

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Lipoma HMGIC fusion partner
Identifiers
Symbol(s) LHFP; MGC22429
External IDs OMIM: 606710 MGI: 1920048 HomoloGene: 4223
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 10186 108927
Ensembl ENSG00000183722 ENSMUSG00000048332
Uniprot Q9Y693 Q8BM86
Refseq NM_005780 (mRNA)
NP_005771 (protein)		 NM_175386 (mRNA)
NP_780595 (protein)
Location Chr 13: 38.82 - 39.08 Mb Chr 3: 53.13 - 53.35 Mb
Pubmed search [1] [2]

Lipoma HMGIC fusion partner, also known as LHFP, is a human gene.[1]

This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. This gene is fused to a high-mobility group gene in a translocation-associated lipoma. Mutations in another LHFP-like gene result in deafness in humans and mice. Alternatively spliced transcript variants have been found; however, their full-length nature is not known.[1]

[edit] References

  1. ^ a b Entrez Gene: LHFP lipoma HMGIC fusion partner.

[edit] Further reading

  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560. 
  • Longo-Guess CM, Gagnon LH, Cook SA, et al. (2005). "A missense mutation in the previously undescribed gene Tmhs underlies deafness in hurry-scurry (hscy) mice.". Proc. Natl. Acad. Sci. U.S.A. 102 (22): 7894–9. doi:10.1073/pnas.0500760102. PMID 15905332. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature 428 (6982): 522–8. doi:10.1038/nature02379. PMID 15057823. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Petit MM, Schoenmakers EF, Huysmans C, et al. (1999). "LHFP, a novel translocation partner gene of HMGIC in a lipoma, is a member of a new family of LHFP-like genes.". Genomics 57 (3): 438–41. doi:10.1006/geno.1999.5778. PMID 10329012. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
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