Levomethamphetamine

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Levomethamphetamine
Systematic (IUPAC) name
(R)-N-methyl-1-phenyl-propan-2-amine
Identifiers
CAS number 537-46-2
ATC code  ?
PubChem 1206
Chemical data
Formula C10H15N 
Mol. mass 149.2
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life  ?
Excretion Renal
Therapeutic considerations
Pregnancy cat.

?

Legal status

OTC

Routes Nasal Inhalation

Levomethamphetamine (other names: l-desoxyephedrine, l-methamphetamine, levmetamfetamine ) is the l- stereoisomer of methamphetamine, a sympathomimetic vasoconstrictor which is the active ingredient used in some over-the-counter nasal decongestants. The common brand-name for levmetamfetamine in the U.S. is the Vicks Inhaler[1]. In the U.S., the name was converted to levmetamfetamine from levo-methamphetamine to lower the risk of abuse of the decongestant preparation.

Contents

[edit] Chemistry

Levomethamphetamine affects the sympathetic nervous system but is not thought to be nearly as addictive or centrally active as the d- isomer of methamphetamine (dextro-methamphetamine, d-methamphetamine, d-desoxyephedrine, etc.) and only exerts vasoconstricting effects used for decongestion.[2]

[edit] Side Effects

Common side effects include muscle tremor and stomach cramps. Other side effects include hypertension and tachycardia.

[edit] Recreational Use

Although levo-methamphetamine is only very mildly centrally active (unlike dextro-methamphetamine, which acts mainly on the central nervous system), recreational drug users may abuse the inhaler preparation by cracking open the inhaler and then swallowing the cotton inside (as the cotton is soaked in levo-methamphetamine.) This gives the user a very mild "speedy" effect with a mild energy boost, similar to that of ephedrine or pseudoephedrine. However, particularly if a solution is made with the cotton in an acidic solution, the initial effects last for less than two hours, with minimal and transient mood lift and stimulation Sometimes uncomfortable and unpleasant feelings can arise by ingesting the cotton, since the cotton is also soaked in menthol and camphor. Both menthol and camphor are analgesics and are possibly lethal at high doses. A common practise in the early to mid 1950's that was similar was were people would break open Benzedrine inhalers and then either swallow the cotton [3]or let it steep in a cup of tea or coffee, swallowing was reffered to as "popping bennies".

[edit] References

  1. ^ Vicks Vapor Inhalor Ingredients Listing & Information Page. Accessed April 3, 2008.
  2. ^ Topical Decongestants Not Requiring an FDA Warning US Pharmacist Vol. No: 31:07 Posted: 7/20/2006. Accessed via internet 04/03/08
  3. ^ Bennies the Menace TIME Magazine Monday, Jun. 14, 1954. Accessed Via Google 4/02/08