Leukoencephalopathy with neuroaxonal spheroids

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Leukoencephalopathy with neuroaxonal spheroids is a special kind of leukoencephalopathy. It is cause of severe and subacute dementia. It is inherited, following an autosomal dominant pattern

It usually presents in childhood but it can also have an adult onset. In this case, it can present MRIs that mimic those of progressive multiple sclerosis[1].

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[edit] References

  1. ^ Keegan BM, Giannini C, Parisi JE, Lucchinetti CF, Boeve BF, Josephs KA.. "Sporadic adult-onset leukoencephalopathy with neuroaxonal spheroids mimicking cerebral MS". Neurology. PMID 18287567.