Talk:Leflunomide

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"Due to the very long half-life of M1 (approx. 2 weeks), a loading dose of 100 mg for 3 days was used in clinical studies to reach steady-state levels of M1 quickly." It may be nit-picking (or not even right!) but a I think a loading dose speeds up the time to the therapeutic range rather than speeds up time to steady state - which is always 4-5 half lives. If anyone agrees why don't you change it? 220.245.21.8 10:21, 27 December 2006 (UTC)drj55