LCN2

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Lipocalin 2 (oncogene 24p3)
PDB rendering based on 1dfv.
Available structures: 1dfv, 1l6m, 1ngl, 1qqs, 1x71, 1x89, 1x8u
Identifiers
Symbol(s) LCN2; NGAL
External IDs OMIM: 600181 MGI: 96757 HomoloGene: 4064
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 3934 16819
Ensembl ENSG00000148346 ENSMUSG00000026822
Uniprot P80188 Q3UE34
Refseq NM_005564 (mRNA)
NP_005555 (protein)		 NM_008491 (mRNA)
NP_032517 (protein)
Location Chr 9: 129.95 - 129.96 Mb Chr 2: 32.21 - 32.21 Mb
Pubmed search [1] [2]

Lipocalin 2 (oncogene 24p3), also known as LCN2, is a gene.


[edit] Further reading

  • Schmidt-Ott KM, Mori K, Li JY, et al. (2007). "Dual action of neutrophil gelatinase-associated lipocalin.". J. Am. Soc. Nephrol. 18 (2): 407-13. doi:10.1681/ASN.2006080882. PMID 17229907. 
  • Triebel S, Bläser J, Reinke H, Tschesche H (1993). "A 25 kDa alpha 2-microglobulin-related protein is a component of the 125 kDa form of human gelatinase.". FEBS Lett. 314 (3): 386-8. PMID 1281792. 
  • Bläser J, Triebel S, Tschesche H (1995). "A sandwich enzyme immunoassay for the determination of neutrophil lipocalin in body fluids.". Clin. Chim. Acta 235 (2): 137-45. PMID 7554268. 
  • Kjeldsen L, Johnsen AH, Sengeløv H, Borregaard N (1993). "Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase.". J. Biol. Chem. 268 (14): 10425-32. PMID 7683678. 
  • Chan P, Simon-Chazottes D, Mattei MG, et al. (1995). "Comparative mapping of lipocalin genes in human and mouse: the four genes for complement C8 gamma chain, prostaglandin-D-synthase, oncogene-24p3, and progestagen-associated endometrial protein map to HSA9 and MMU2.". Genomics 23 (1): 145-50. doi:10.1006/geno.1994.1470. PMID 7829063. 
  • Bartsch S, Tschesche H (1995). "Cloning and expression of human neutrophil lipocalin cDNA derived from bone marrow and ovarian cancer cells.". FEBS Lett. 357 (3): 255-9. PMID 7835423. 
  • Xu SY, Carlson M, Engström A, et al. (1995). "Purification and characterization of a human neutrophil lipocalin (HNL) from the secondary granules of human neutrophils.". Scand. J. Clin. Lab. Invest. 54 (5): 365-76. PMID 7997842. 
  • Bundgaard JR, Sengeløv H, Borregaard N, Kjeldsen L (1994). "Molecular cloning and expression of a cDNA encoding NGAL: a lipocalin expressed in human neutrophils.". Biochem. Biophys. Res. Commun. 202 (3): 1468-75. doi:10.1006/bbrc.1994.2096. PMID 8060329. 
  • Xu SY, Petersson CG, Carlson M, Venge P (1994). "The development of an assay for human neutrophil lipocalin (HNL)--to be used as a specific marker of neutrophil activity in vivo and vitro.". J. Immunol. Methods 171 (2): 245-52. PMID 8195592. 
  • Axelsson L, Bergenfeldt M, Ohlsson K (1996). "Studies of the release and turnover of a human neutrophil lipocalin.". Scand. J. Clin. Lab. Invest. 55 (7): 577-88. PMID 8633182. 
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548. 
  • Cowland JB, Borregaard N (1997). "Molecular characterization and pattern of tissue expression of the gene for neutrophil gelatinase-associated lipocalin from humans.". Genomics 45 (1): 17-23. doi:10.1006/geno.1997.4896. PMID 9339356. 
  • Stoesz SP, Friedl A, Haag JD, et al. (1998). "Heterogeneous expression of the lipocalin NGAL in primary breast cancers.". Int. J. Cancer 79 (6): 565-72. PMID 9842963. 
  • Coles M, Diercks T, Muehlenweg B, et al. (1999). "The solution structure and dynamics of human neutrophil gelatinase-associated lipocalin.". J. Mol. Biol. 289 (1): 139-57. doi:10.1006/jmbi.1999.2755. PMID 10339412. 
  • Friedl A, Stoesz SP, Buckley P, Gould MN (1999). "Neutrophil gelatinase-associated lipocalin in normal and neoplastic human tissues. Cell type-specific pattern of expression.". Histochem. J. 31 (7): 433-41. PMID 10475571. 
  • Rudd PM, Mattu TS, Masure S, et al. (1999). "Glycosylation of natural human neutrophil gelatinase B and neutrophil gelatinase B-associated lipocalin.". Biochemistry 38 (42): 13937-50. PMID 10529240. 
  • Goetz DH, Willie ST, Armen RS, et al. (2000). "Ligand preference inferred from the structure of neutrophil gelatinase associated lipocalin.". Biochemistry 39 (8): 1935-41. PMID 10684642. 
  • Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491-6. PMID 10737800. 
  • Zerega B, Cermelli S, Michelis B, et al. (2000). "Expression of NRL/NGAL (neu-related lipocalin/neutrophil gelatinase-associated lipocalin) during mammalian embryonic development and in inflammation.". Eur. J. Cell Biol. 79 (3): 165-72. PMID 10777108. 
  • Devireddy LR, Teodoro JG, Richard FA, Green MR (2001). "Induction of apoptosis by a secreted lipocalin that is transcriptionally regulated by IL-3 deprivation.". Science 293 (5531): 829-34. doi:10.1126/science.1061075. PMID 11486081. 
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