Laminin, alpha 1

From Wikipedia, the free encyclopedia

Laminin, alpha 1

Identifiers

External IDs

OMIM: 150320 MGI: 99892 HomoloGene: 21146

Gene ontology
Molecular Function:	• receptor binding • extracellular matrix structural constituent
Cellular Component:	• basement membrane • laminin-1 complex • laminin-3 complex
Biological Process:	• multicellular organismal development • regulation of cell adhesion • regulation of cell migration • regulation of embryonic development • positive regulation of epithelial cell proliferation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

XM_001130075 (mRNA)
XP_001130075 (protein)

NM_008480 (mRNA)
NP_032506 (protein)

Location

Chr 18: 6.93 - 7.11 Mb

Chr 17: 67.6 - 67.73 Mb

Pubmed search

[1]

[2]

Laminin, alpha 1, also known as LAMA1, is a human gene.^[1]

[edit] References

^ Entrez Gene: LAMA1 laminin, alpha 1.

[edit] Further reading

Haaparanta T, Uitto J, Ruoslahti E, Engvall E (1991). "Molecular cloning of the cDNA encoding human laminin A chain.". Matrix 11 (3): 151-60. PMID 1714537.
Nissinen M, Vuolteenaho R, Boot-Handford R, et al. (1991). "Primary structure of the human laminin A chain. Limited expression in human tissues.". Biochem. J. 276 ( Pt 2): 369-79. PMID 2049067.
Taraboletti G, Rao CN, Krutzsch HC, et al. (1990). "Sulfatide-binding domain of the laminin A chain.". J. Biol. Chem. 265 (21): 12253-8. PMID 2373692.
Nagayoshi T, Mattei MG, Passage E, et al. (1990). "Human laminin A chain (LAMA) gene: chromosomal mapping to locus 18p11.3.". Genomics 5 (4): 932-5. PMID 2591971.
Olsen D, Nagayoshi T, Fazio M, et al. (1989). "Human laminin: cloning and sequence analysis of cDNAs encoding A, B1 and B2 chains, and expression of the corresponding genes in human skin and cultured cells.". Lab. Invest. 60 (6): 772-82. PMID 2733383.
Leivo I, Engvall E (1986). "C3d fragment of complement interacts with laminin and binds to basement membranes of glomerulus and trophoblast.". J. Cell Biol. 103 (3): 1091-100. PMID 3488995.
Wewer UM, Gerecke DR, Durkin ME, et al. (1995). "Human beta 2 chain of laminin (formerly S chain): cDNA cloning, chromosomal localization, and expression in carcinomas.". Genomics 24 (2): 243-52. doi:10.1006/geno.1994.1612. PMID 7698745.
Yamada H, Shimizu T, Tanaka T, et al. (1994). "Dystroglycan is a binding protein of laminin and merosin in peripheral nerve.". FEBS Lett. 352 (1): 49-53. PMID 7925941.
Moser TL, Enghild JJ, Pizzo SV, Stack MS (1993). "The extracellular matrix proteins laminin and fibronectin contain binding domains for human plasminogen and tissue plasminogen activator.". J. Biol. Chem. 268 (25): 18917-23. PMID 8360181.
Yurchenco PD, Sung U, Ward MD, et al. (1993). "Recombinant laminin G domain mediates myoblast adhesion and heparin binding.". J. Biol. Chem. 268 (11): 8356-65. PMID 8463343.
Ancsin JB, Kisilevsky R (1997). "Characterization of high affinity binding between laminin and the acute-phase protein, serum amyloid A.". J. Biol. Chem. 272 (1): 406-13. PMID 8995276.
Zahedi K (1997). "Characterization of the binding of serum amyloid P to laminin.". J. Biol. Chem. 272 (4): 2143-8. PMID 8999915.
Utani A, Nomizu M, Yamada Y (1997). "Fibulin-2 binds to the short arms of laminin-5 and laminin-1 via conserved amino acid sequences.". J. Biol. Chem. 272 (5): 2814-20. PMID 9006922.
Cáceres J, Brandan E (1997). "Interaction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycans.". J. Cell. Biochem. 65 (2): 145-58. PMID 9136074.
Chen M, Marinkovich MP, Veis A, et al. (1997). "Interactions of the amino-terminal noncollagenous (NC1) domain of type VII collagen with extracellular matrix components. A potential role in epidermal-dermal adherence in human skin.". J. Biol. Chem. 272 (23): 14516-22. PMID 9169408.
Schuger L, Skubitz AP, Zhang J, et al. (1997). "Laminin alpha1 chain synthesis in the mouse developing lung: requirement for epithelial-mesenchymal contact and possible role in bronchial smooth muscle development.". J. Cell Biol. 139 (2): 553-62. PMID 9334356.
Mrowiec T, Melchar C, Górski A (1998). "HIV-protein-mediated alterations in T cell interactions with the extracellular matrix proteins and endothelium.". Arch. Immunol. Ther. Exp. (Warsz.) 45 (2-3): 255-9. PMID 9597096.
O'Grady P, Thai TC, Saito H (1998). "The laminin-nidogen complex is a ligand for a specific splice isoform of the transmembrane protein tyrosine phosphatase LAR.". J. Cell Biol. 141 (7): 1675-84. PMID 9647658.
Ettner N, Göhring W, Sasaki T, et al. (1998). "The N-terminal globular domain of the laminin alpha1 chain binds to alpha1beta1 and alpha2beta1 integrins and to the heparan sulfate-containing domains of perlecan.". FEBS Lett. 430 (3): 217-21. PMID 9688542.
Ludwig HC, Rausch S, Schallock K, Markakis E (1999). "Expression of CD 73 (ecto-5'-nucleotidase) in 165 glioblastomas by immunohistochemistry and electronmicroscopic histochemistry.". Anticancer Res. 19 (3A): 1747-52. PMID 10470109.