Lactate aldolase

From Wikipedia, the free encyclopedia

In enzymology, a lactate aldolase (EC 4.1.2.36) is an enzyme that catalyzes the chemical reaction

(S)-lactate formate + acetaldehyde

Hence, this enzyme has one substrate, (S)-lactate, and two products, formate and acetaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (S)-lactate acetaldehyde-lyase (formate-forming). Other names in common use include lactate synthase, and (S)-lactate acetaldehyde-lyase. This enzyme participates in pyruvate metabolism.

[edit] References

• IUBMB entry for 4.1.2.36
• BRENDA references for 4.1.2.36 (Recommended.)
• PubMed references for 4.1.2.36
• PubMed Central references for 4.1.2.36
• Google Scholar references for 4.1.2.36
• Gulyi MF, Silonova NV (1987). "[Various metabolic reactions of formate in animal tissues]". Ukr. Biokhim. Zh. 59: 29–35. PMID 3629727. 

[edit] External links

The CAS registry number for this enzyme class is 110777-33-8.

• IUBMB entry for 4.1.2.36

• KEGG entry for 4.1.2.36

• BRENDA entry for 4.1.2.36

• NiceZyme view of 4.1.2.36

• EC2PDB: PDB structures for 4.1.2.36

• PRIAM entry for 4.1.2.36

• PUMA2 entry for 4.1.2.36

• IntEnz: Integrated Enzyme entry for 4.1.2.36

• MetaCyc entry for 4.1.2.36

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050041: lactate aldolase

• AMIGO entry for GO code 0050041: lactate aldolase