L-seryl-tRNASec selenium transferase

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In enzymology, a L-seryl-tRNASec selenium transferase (EC 2.9.1.1) is an enzyme that catalyzes the chemical reaction

L-seryl-tRNASec + selenophosphate L-selenocysteinyl-tRNASec + phosphate

Thus, the two substrates of this enzyme are L-seryl-tRNASec and selenophosphate, whereas its two products are L-selenocysteinyl-tRNASec and phosphate.

This enzyme belongs to the family of transferases, specifically those transferring selenium-containing groups selenotransferases. The systematic name of this enzyme class is selenophosphate:L-seryl-tRNASec selenium transferase. Other names in common use include L-selenocysteinyl-tRNASel synthase, L-selenocysteinyl-tRNASec synthase selenocysteine synthase, cysteinyl-tRNASec-selenium transferase, and cysteinyl-tRNASec-selenium transferase. This enzyme participates in selenoamino acid metabolism. It employs one cofactor, pyridoxal phosphate.

[edit] References

• IUBMB entry for 2.9.1.1
• BRENDA references for 2.9.1.1 (Recommended.)
• PubMed references for 2.9.1.1
• PubMed Central references for 2.9.1.1
• Google Scholar references for 2.9.1.1
• Forchhammer K, Bock A (1991). "Selenocysteine synthase from Escherichia coli. Analysis of the reaction sequence". J. Biol. Chem. 266: 6324–8. PMID 2007585. 

[edit] External links

• IUBMB entry for 2.9.1.1

• KEGG entry for 2.9.1.1

• BRENDA entry for 2.9.1.1

• NiceZyme view of 2.9.1.1

• EC2PDB: PDB structures for 2.9.1.1

• PRIAM entry for 2.9.1.1

• PUMA2 entry for 2.9.1.1

• IntEnz: Integrated Enzyme entry for 2.9.1.1

• MetaCyc entry for 2.9.1.1

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0004125: L-seryl-tRNASec selenium transferase

• AMIGO entry for GO code 0004125: L-seryl-tRNASec selenium transferase