L-pipecolate oxidase

From Wikipedia, the free encyclopedia

In enzymology, a L-pipecolate oxidase (EC 1.5.3.7) is an enzyme that catalyzes the chemical reaction

L-pipecolate + O₂ 2,3,4,5-tetrahydropyridine-2-carboxylate + H₂O₂

Thus, the two substrates of this enzyme are L-pipecolate and O₂, whereas its two products are 2,3,4,5-tetrahydropyridine-2-carboxylate and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with oxygen as acceptor. The systematic name of this enzyme class is L-pipecolate:oxygen 1,6-oxidoreductase. Other names in common use include pipecolate oxidase, and L-pipecolic acid oxidase. This enzyme participates in lysine degradation.

[edit] References

• IUBMB entry for 1.5.3.7
• BRENDA references for 1.5.3.7 (Recommended.)
• PubMed references for 1.5.3.7
• PubMed Central references for 1.5.3.7
• Google Scholar references for 1.5.3.7
• Baginsky ML, Rodwell VW (1967). "Metabolism of pipecolic acid in a Pseudomonas species. V. Pipecolate oxidase and dehydrogenase". J. Bacteriol. 94: 1034–9. PMID 6051341. 
• Kinzel JJ, Bhattacharjee JK (1982). "Lysine biosynthesis in Rhodotorula glutinis: properties of pipecolic acid oxidase". J. Bacteriol. 151: 1073–7. PMID 6809728. 

[edit] External links

The CAS registry number for this enzyme class is 81669-65-0.

• IUBMB entry for 1.5.3.7

• KEGG entry for 1.5.3.7

• BRENDA entry for 1.5.3.7

• NiceZyme view of 1.5.3.7

• EC2PDB: PDB structures for 1.5.3.7

• PRIAM entry for 1.5.3.7

• PUMA2 entry for 1.5.3.7

• IntEnz: Integrated Enzyme entry for 1.5.3.7

• MetaCyc entry for 1.5.3.7

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050031: L-pipecolate oxidase

• AMIGO entry for GO code 0050031: L-pipecolate oxidase