L-pipecolate dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a L-pipecolate dehydrogenase (EC 1.5.99.3) is an enzyme that catalyzes the chemical reaction

L-pipecolate + acceptor 2,3,4,5-tetrahydropyridine-2-carboxylate + reduced acceptor

Thus, the two substrates of this enzyme are L-pipecolate and acceptor, whereas its two products are 2,3,4,5-tetrahydropyridine-2-carboxylate and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with other acceptors. The systematic name of this enzyme class is L-pipecolate:acceptor 1,6-oxidoreductase. This enzyme is also called L-pipecolate:(acceptor) 1,6-oxidoreductase. This enzyme participates in lysine degradation.

[edit] References

• IUBMB entry for 1.5.99.3
• BRENDA references for 1.5.99.3 (Recommended.)
• PubMed references for 1.5.99.3
• PubMed Central references for 1.5.99.3
• Google Scholar references for 1.5.99.3
• Baginsky ML, Rodwell VW (1967). "Metabolism of pipecolic acid in a Pseudomonas species. V. Pipecolate oxidase and dehydrogenase". J. Bacteriol. 94: 1034–9. PMID 6051341. 

[edit] External links

The CAS registry number for this enzyme class is 9076-63-5.

• IUBMB entry for 1.5.99.3

• KEGG entry for 1.5.99.3

• BRENDA entry for 1.5.99.3

• NiceZyme view of 1.5.99.3

• EC2PDB: PDB structures for 1.5.99.3

• PRIAM entry for 1.5.99.3

• PUMA2 entry for 1.5.99.3

• IntEnz: Integrated Enzyme entry for 1.5.99.3

• MetaCyc entry for 1.5.99.3

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050030: L-pipecolate dehydrogenase

• AMIGO entry for GO code 0050030: L-pipecolate dehydrogenase