L-cysteate sulfo-lyase

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In enzymology, a L-cysteate sulfo-lyase (EC 4.4.1.25) is an enzyme that catalyzes the chemical reaction

L-cysteate + H₂O pyruvate + bisulfite + NH₃

Thus, the two substrates of this enzyme are L-cysteate and H₂O, whereas its 3 products are pyruvate, bisulfite, and NH₃.

This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is L-cysteate bisulfite-lyase (deaminating; pyruvate-forming). Other names in common use include L-cysteate sulfo-lyase (deaminating), and CuyA.

[edit] References

• IUBMB entry for 4.4.1.25
• BRENDA references for 4.4.1.25 (Recommended.)
• PubMed references for 4.4.1.25
• PubMed Central references for 4.4.1.25
• Google Scholar references for 4.4.1.25
• Denger K, Smits TH, Cook AM (2006). "L-cysteate sulpho-lyase, a widespread pyridoxal 5'-phosphate-coupled desulphonative enzyme purified from Silicibacter pomeroyi DSS-3(T)". Biochem. J. 394: 657–64. doi:10.1042/BJ20051311. PMID 16302849. 

[edit] External links

• IUBMB entry for 4.4.1.25

• KEGG entry for 4.4.1.25

• BRENDA entry for 4.4.1.25

• NiceZyme view of 4.4.1.25

• EC2PDB: PDB structures for 4.4.1.25

• PRIAM entry for 4.4.1.25

• PUMA2 entry for 4.4.1.25

• IntEnz: Integrated Enzyme entry for 4.4.1.25

• MetaCyc entry for 4.4.1.25

• Atomic-resolution structures of enzymes belonging to this class