L-ascorbate-cytochrome-b5 reductase

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In enzymology, a L-ascorbate---cytochrome-b5 reductase (EC 1.10.2.1) is an enzyme that catalyzes the chemical reaction

L-ascorbate + ferricytochrome b₅ monodehydroascorbate + ferrocytochrome b₅ + H⁺

Thus, the two substrates of this enzyme are L-ascorbate and ferricytochrome b5, whereas its 3 products are monodehydroascorbate, ferrocytochrome b5, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on diphenols and related substances as donor with a cytochrome as acceptor. The systematic name of this enzyme class is L-ascorbate:ferricytochrome-b5 oxidoreductase. This enzyme is also called ascorbate-cytochrome b5 reductase.

[edit] References

• IUBMB entry for 1.10.2.1
• BRENDA references for 1.10.2.1 (Recommended.)
• PubMed references for 1.10.2.1
• PubMed Central references for 1.10.2.1
• Google Scholar references for 1.10.2.1
• Everling FB, Weis W, Staudinger H (1969). "[Kinetic studies on an ascorbate: ferricytochrome b5 oxidoreductase (EC 1.1.2.?)]". Hoppe. Seylers. Z. Physiol. Chem. 350: 1485–92. PMID 5363650. 

[edit] External links

The CAS registry number for this enzyme class is 37237-57-3.

• IUBMB entry for 1.10.2.1

• KEGG entry for 1.10.2.1

• BRENDA entry for 1.10.2.1

• NiceZyme view of 1.10.2.1

• EC2PDB: PDB structures for 1.10.2.1

• PRIAM entry for 1.10.2.1

• PUMA2 entry for 1.10.2.1

• IntEnz: Integrated Enzyme entry for 1.10.2.1

• MetaCyc entry for 1.10.2.1

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047063: L-ascorbate-cytochrome-b5 reductase

• AMIGO entry for GO code 0047063: L-ascorbate-cytochrome-b5 reductase