L-arabinonate dehydratase

From Wikipedia, the free encyclopedia

In enzymology, a L-arabinonate dehydratase (EC 4.2.1.25) is an enzyme that catalyzes the chemical reaction

L-arabinonate 2-dehydro-3-deoxy-L-arabinonate + H₂O

Hence, this enzyme has one substrate, L-arabinonate, and two products, 2-dehydro-3-deoxy-L-arabinonate and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is L-arabinonate hydro-lyase (2-dehydro-3-deoxy-L-arabinonate-forming). Other names in common use include L-arabonate dehydrase, L-arabonate dehydratase, and L-arabinonate hydro-lyase. This enzyme participates in ascorbate and aldarate metabolism.

[edit] References

• IUBMB entry for 4.2.1.25
• BRENDA references for 4.2.1.25 (Recommended.)
• PubMed references for 4.2.1.25
• PubMed Central references for 4.2.1.25
• Google Scholar references for 4.2.1.25
• WEIMBERG R (1959). "L-2-Keto-4,5-dihydroxyvaleric acid: an intermediate in the oxidation of L-arabinose by Pseudomonas saccharophila". J. Biol. Chem. 234: 727–32. PMID 13654251. 

[edit] External links

The CAS registry number for this enzyme class is 9024-30-0.

• IUBMB entry for 4.2.1.25

• KEGG entry for 4.2.1.25

• BRENDA entry for 4.2.1.25

• NiceZyme view of 4.2.1.25

• EC2PDB: PDB structures for 4.2.1.25

• PRIAM entry for 4.2.1.25

• PUMA2 entry for 4.2.1.25

• IntEnz: Integrated Enzyme entry for 4.2.1.25

• MetaCyc entry for 4.2.1.25

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050020: L-arabinonate dehydratase

• AMIGO entry for GO code 0050020: L-arabinonate dehydratase