L-arabinitol 4-dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a L-arabinitol 4-dehydrogenase (EC 1.1.1.12) is an enzyme that catalyzes the chemical reaction

L-arabinitol + NAD⁺ L-xylulose + NADH + H⁺

Thus, the two substrates of this enzyme are L-arabinitol and NAD⁺, whereas its 3 products are L-xylulose, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-arabinitol:NAD+ 4-oxidoreductase (L-xylulose-forming). Other names in common use include pentitol-DPN dehydrogenase, and L-arabitol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions.

[edit] References

• IUBMB entry for 1.1.1.12
• BRENDA references for 1.1.1.12 (Recommended.)
• PubMed references for 1.1.1.12
• PubMed Central references for 1.1.1.12
• Google Scholar references for 1.1.1.12
• CHIANG C, KNIGHT SG (1960). "A new pathway of pentose metabolism". Biochem. Biophys. Res. Commun. 3: 554–9. doi:10.1016/0006-291X(60)90174-1. PMID 13692998. 
• CHIANG C, KNIGHT SG (1961). "L-Arabinose metabolism by cell-free extracts of Penicillium chrysogenum". Biochim. Biophys. Acta. 46: 271–8. doi:10.1016/0006-3002(61)90750-8. PMID 13692999. 

[edit] External links

The CAS registry number for this enzyme class is 9028-19-7.

• IUBMB entry for 1.1.1.12

• KEGG entry for 1.1.1.12

• BRENDA entry for 1.1.1.12

• NiceZyme view of 1.1.1.12

• EC2PDB: PDB structures for 1.1.1.12

• PRIAM entry for 1.1.1.12

• PUMA2 entry for 1.1.1.12

• IntEnz: Integrated Enzyme entry for 1.1.1.12

• MetaCyc entry for 1.1.1.12

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050019: L-arabinitol 4-dehydrogenase

• AMIGO entry for GO code 0050019: L-arabinitol 4-dehydrogenase