L-amino-acid dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a L-amino-acid dehydrogenase (EC 1.4.1.5) is an enzyme that catalyzes the chemical reaction

an L-amino acid + H₂O + NAD⁺ a 2-oxo acid + NH₃ + NADH + H⁺

The 3 substrates of this enzyme are L-amino acid, H₂O, and NAD⁺, whereas its 4 products are 2-oxo acid, NH₃, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-amino-acid:NAD+ oxidoreductase (deaminating).

[edit] References

• IUBMB entry for 1.4.1.5
• BRENDA references for 1.4.1.5 (Recommended.)
• PubMed references for 1.4.1.5
• PubMed Central references for 1.4.1.5
• Google Scholar references for 1.4.1.5
• Nisman B and Mager J (Lond.). "Diphosphopyridine nucleotide and phosphate requirement for oxidation of amino-acids by cell-free extracts of obligate anaerobes". N Nature: 243–244. 

[edit] External links

The CAS registry number for this enzyme class is 9029-13-4.

• IUBMB entry for 1.4.1.5

• KEGG entry for 1.4.1.5

• BRENDA entry for 1.4.1.5

• NiceZyme view of 1.4.1.5

• EC2PDB: PDB structures for 1.4.1.5

• PRIAM entry for 1.4.1.5

• PUMA2 entry for 1.4.1.5

• IntEnz: Integrated Enzyme entry for 1.4.1.5

• MetaCyc entry for 1.4.1.5

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050018: L-amino-acid dehydrogenase

• AMIGO entry for GO code 0050018: L-amino-acid dehydrogenase