Kynurenine-glyoxylate transaminase

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In enzymology, a kynurenine-glyoxylate transaminase (EC 2.6.1.63) is an enzyme that catalyzes the chemical reaction

L-kynurenine + glyoxylate 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine

Thus, the two substrates of this enzyme are L-kynurenine and glyoxylate, whereas its two products are 4-(2-aminophenyl)-2,4-dioxobutanoate and glycine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-kynurenine:glyoxylate aminotransferase (cyclizing). This enzyme is also called kynurenine-glyoxylate aminotransferase.

[edit] References

• IUBMB entry for 2.6.1.63
• BRENDA references for 2.6.1.63 (Recommended.)
• PubMed references for 2.6.1.63
• PubMed Central references for 2.6.1.63
• Google Scholar references for 2.6.1.63
• Harada I (1980). "[Glucagen inducible kynurenine aminotransferase.]". Wakayama Igaku 31: 61–68. 

[edit] External links

The CAS registry number for this enzyme class is 74506-33-5.

• IUBMB entry for 2.6.1.63

• KEGG entry for 2.6.1.63

• BRENDA entry for 2.6.1.63

• NiceZyme view of 2.6.1.63

• EC2PDB: PDB structures for 2.6.1.63

• PRIAM entry for 2.6.1.63

• PUMA2 entry for 2.6.1.63

• IntEnz: Integrated Enzyme entry for 2.6.1.63

• MetaCyc entry for 2.6.1.63

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047315: kynurenine-glyoxylate transaminase

• AMIGO entry for GO code 0047315: kynurenine-glyoxylate transaminase