KRT36

From Wikipedia, the free encyclopedia

Keratin 36

Identifiers

KRT36; HA6; KRTHA6; hHa6

External IDs

Gene ontology
Molecular Function:	• structural molecule activity • structural constituent of epidermis
Cellular Component:	• cellular_component • intermediate filament
Biological Process:	• biological_process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

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Refseq

NM_003771 (mRNA)
NP_003762 (protein)

n/a (mRNA)
n/a (protein)

Location

Chr 17: 36.9 - 36.9 Mb

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Pubmed search

[1]

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Keratin 36, also known as KRT36, is a human gene.^[1]

The protein encoded by this gene is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.^[1]

[edit] References

^ ^a ^b Entrez Gene: KRT36 keratin 36.

[edit] Further reading

Fuchs E, Weber K (1994). "Intermediate filaments: structure, dynamics, function, and disease.". Annu. Rev. Biochem. 63: 345-82. doi:10.1146/annurev.bi.63.070194.002021. PMID 7979242.
Yu J, Yu DW, Checkla DM, et al. (1993). "Human hair keratins.". J. Invest. Dermatol. 101 (1 Suppl): 56S-59S. PMID 7686952.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Schweizer J, Bowden PE, Coulombe PA, et al. (2006). "New consensus nomenclature for mammalian keratins.". J. Cell Biol. 174 (2): 169-74. doi:10.1083/jcb.200603161. PMID 16831889.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Langbein L, Rogers MA, Winter H, et al. (1999). "The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.". J. Biol. Chem. 274 (28): 19874-84. PMID 10391933.
Rogers MA, Winter H, Wolf C, et al. (1998). "Characterization of a 190-kilobase pair domain of human type I hair keratin genes.". J. Biol. Chem. 273 (41): 26683-91. PMID 9756910.