KRT33B

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Keratin 33B
Identifiers
Symbol(s) KRT33B; KRTHA3A; HA3II; Ha-3II; KRTHA3B; hHa3-II
External IDs OMIM: 602762 MGI: 1309991 HomoloGene: 74434
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 3884 16671
Ensembl ENSG00000131738 n/a
Uniprot Q14525 n/a
Refseq NM_002279 (mRNA)
NP_002270 (protein)		 XM_904709 (mRNA)
XP_909802 (protein)
Location Chr 17: 36.77 - 36.78 Mb n/a
Pubmed search [1] [2]

Keratin 33B, also known as KRT33B, is a human gene.[1]

The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRTHA3A and KRTHA3B.[1]

[edit] References

  1. ^ a b Entrez Gene: KRT33B keratin 33B.

[edit] Further reading

  • Yu J, Yu DW, Checkla DM, et al. (1993). "Human hair keratins.". J. Invest. Dermatol. 101 (1 Suppl): 56S-59S. PMID 7686952. 
  • Rogers MA, Schweizer J, Kreig T, Winter H (1995). "A novel human type I hair keratin gene: evidence for two keratin hHa3 isoforms.". Mol. Biol. Rep. 20 (3): 155-61. PMID 7565656. 
  • Rogers MA, Winter H, Wolf C, et al. (1998). "Characterization of a 190-kilobase pair domain of human type I hair keratin genes.". J. Biol. Chem. 273 (41): 26683-91. PMID 9756910. 
  • Langbein L, Rogers MA, Winter H, et al. (1999). "The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.". J. Biol. Chem. 274 (28): 19874-84. PMID 10391933. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Anderson NL, Polanski M, Pieper R, et al. (2004). "The human plasma proteome: a nonredundant list developed by combination of four separate sources.". Mol. Cell Proteomics 3 (4): 311-26. doi:10.1074/mcp.M300127-MCP200. PMID 14718574. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Schweizer J, Bowden PE, Coulombe PA, et al. (2006). "New consensus nomenclature for mammalian keratins.". J. Cell Biol. 174 (2): 169-74. doi:10.1083/jcb.200603161. PMID 16831889. 
  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931. 
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