KRT23

From Wikipedia, the free encyclopedia


Keratin 23 (histone deacetylase inducible)
Identifiers
Symbol(s) KRT23; CK23; DKFZP434G032; HAIK1; K23; MGC26158
External IDs OMIM: 606194 MGI: 2148866 HomoloGene: 9172
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 25984 94179
Ensembl ENSG00000108244 ENSMUSG00000006777
Uniprot Q9C075 Q3ULX3
Refseq NM_015515 (mRNA)
NP_056330 (protein)		 XM_994630 (mRNA)
XP_999724 (protein)
Location Chr 17: 36.33 - 36.35 Mb Chr 11: 99.29 - 99.31 Mb
Pubmed search [1] [2]

Keratin 23 (histone deacetylase inducible), also known as KRT23, is a human gene.[1]

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.[1]

[edit] References

  1. ^ a b Entrez Gene: KRT23 keratin 23 (histone deacetylase inducible).

[edit] Further reading

  • Schweizer J, Bowden PE, Coulombe PA, et al. (2006). "New consensus nomenclature for mammalian keratins.". J. Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMID 16831889. 
  • Suzuki A, Ji G, Numabe Y, et al. (2004). "Single nucleotide polymorphisms associated with aggressive periodontitis and severe chronic periodontitis in Japanese.". Biochem. Biophys. Res. Commun. 317 (3): 887–92. doi:10.1016/j.bbrc.2004.03.126. PMID 15081423. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Tolstonog GV, Sabasch M, Traub P (2002). "Cytoplasmic intermediate filaments are stably associated with nuclear matrices and potentially modulate their DNA-binding function.". DNA Cell Biol. 21 (3): 213–39. doi:10.1089/10445490252925459. PMID 12015898. 
  • Hesse M, Magin TM, Weber K (2002). "Genes for intermediate filament proteins and the draft sequence of the human genome: novel keratin genes and a surprisingly high number of pseudogenes related to keratin genes 8 and 18.". J. Cell. Sci. 114 (Pt 14): 2569–75. PMID 11683385. 
  • Zhang JS, Wang L, Huang H, et al. (2001). "Keratin 23 (K23), a novel acidic keratin, is highly induced by histone deacetylase inhibitors during differentiation of pancreatic cancer cells.". Genes Chromosomes Cancer 30 (2): 123–35. PMID 11135429. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
 This article on a gene on chromosome 17 is a stub. You can help Wikipedia by expanding it.