KPTN

From Wikipedia, the free encyclopedia

Kaptin (actin binding protein)

Identifiers

External IDs

Gene ontology
Molecular Function:	• actin binding
Cellular Component:	• nucleus • microtubule organizing center • actin cytoskeleton
Biological Process:	• cell motility • actin filament organization • blood coagulation • sensory perception of sound

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_007059 (mRNA)
NP_008990 (protein)

NM_133727 (mRNA)
NP_598488 (protein)

Location

Chr 19: 52.67 - 52.68 Mb

Chr 7: 15.28 - 15.29 Mb

Pubmed search

[1]

[2]

Kaptin (actin binding protein), also known as KPTN, is a human gene.^[1]

[edit] References

^ Entrez Gene: KPTN kaptin (actin binding protein).

[edit] Further reading

Bearer EL, Prakash JM, Li Z (2002). "Actin dynamics in platelets.". Int. Rev. Cytol. 217: 137–82. PMID 12019562.
Bearer EL (1992). "An actin-associated protein present in the microtubule organizing center and the growth cones of PC-12 cells.". J. Neurosci. 12 (3): 750–61. PMID 1372044.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Bearer EL, Abraham MT (1999). "2E4 (kaptin): a novel actin-associated protein from human blood platelets found in lamellipodia and the tips of the stereocilia of the inner ear.". Eur. J. Cell Biol. 78 (2): 117–26. PMID 10099934.
Bearer EL, Chen AF, Chen AH, et al. (2001). "2E4/Kaptin (KPTN)--a candidate gene for the hearing loss locus, DFNA4.". Ann. Hum. Genet. 64 (Pt 3): 189–96. PMID 11409409.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.