Kinase insert domain receptor

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Kinase insert domain receptor (a type III receptor tyrosine kinase)
Available structures: 1y6a, 1y6b
Identifiers
Symbol(s) KDR; CD309; FLK1; VEGFR; VEGFR2
External IDs OMIM: 191306 MGI96683 HomoloGene55639
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 3791 16542
Ensembl ENSG00000128052 ENSMUSG00000062960
Uniprot P35968 Q3UQZ6
Refseq NM_002253 (mRNA)
NP_002244 (protein)
XM_984991 (mRNA)
XP_990085 (protein)
Location Chr 4: 55.64 - 55.69 Mb Chr 5: 76.21 - 76.26 Mb
Pubmed search [1] [2]

Kinase insert domain receptor (a type III receptor tyrosine kinase) is a VEGF receptor. KDR is the human gene encoding it. KDR has also been designated as CD309 (cluster of differentiation 309).


[edit] See also

[edit] Further reading

  • Petrova TV, Makinen T, Alitalo K (1999). "Signaling via vascular endothelial growth factor receptors.". Exp. Cell Res. 253 (1): 117–30. doi:10.1006/excr.1999.4707. PMID 10579917. 
  • Sato Y, Kanno S, Oda N, et al. (2000). "Properties of two VEGF receptors, Flt-1 and KDR, in signal transduction.". Ann. N. Y. Acad. Sci. 902: 201–5; discussion 205–7. PMID 10865839. 
  • Zachary I, Gliki G (2001). "Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family.". Cardiovasc. Res. 49 (3): 568–81. PMID 11166270. 
  • Vené R, Benelli R, Noonan DM, Albini A (2001). "HIV-Tat dependent chemotaxis and invasion, key aspects of tat mediated pathogenesis.". Clin. Exp. Metastasis 18 (7): 533–8. PMID 11688957. 
  • Lenton K (2003). "VEGFR-2 (KDR/Flk-1).". J. Biol. Regul. Homeost. Agents 16 (3): 227–32. PMID 12456025. 
  • Matsumoto T, Mugishima H (2006). "Signal transduction via vascular endothelial growth factor (VEGF) receptors and their roles in atherogenesis.". J. Atheroscler. Thromb. 13 (3): 130–5. PMID 16835467. 

[edit] External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.