KIF1B

From Wikipedia, the free encyclopedia

Kinesin family member 1B

Identifiers

KIF1B; CMT2; CMT2A; CMT2A1; FLJ23699; HMSNII; KIAA0591; KIAA1448; KLP; MGC134844

External IDs

OMIM: 605995 MGI: 108426 HomoloGene: 69177

Gene ontology
Molecular Function:	• nucleotide binding • microtubule motor activity • protein binding • ATP binding • microtubule binding • ATPase activity • kinesin binding
Cellular Component:	• mitochondrion • microtubule • microtubule associated complex • cytoplasmic vesicle membrane
Biological Process:	• microtubule-based movement • nerve-nerve synaptic transmission • neuromuscular synaptic transmission • anterograde axon cargo transport • embryonic development

Orthologs

Human

Mouse

Refseq

NM_015074 (mRNA)
NP_055889 (protein)

NM_008441 (mRNA)
NP_032467 (protein)

Location

Chr 1: 10.19 - 10.36 Mb

Chr 4: 148.02 - 148.15 Mb

Pubmed search

[1]

[2]

Kinesin family member 1B, also known as KIF1B, is a human gene.^[1]

[edit] References

^ Entrez Gene: KIF1B kinesin family member 1B.

[edit] Further reading

Nangaku M, Sato-Yoshitake R, Okada Y, et al. (1995). "KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria.". Cell 79 (7): 1209-20. PMID 7528108.
Gong TL, Burmeister M, Lomax MI (1997). "The novel gene D4Mil1e maps to mouse chromosome 4 and human chromosome 1p36.". Mamm. Genome 7 (10): 790-1. PMID 8854876.
Saito M, Hayashi Y, Suzuki T, et al. (1998). "Linkage mapping of the gene for Charcot-Marie-Tooth disease type 2 to chromosome 1p (CMT2A) and the clinical features of CMT2A.". Neurology 49 (6): 1630-5. PMID 9409358.
Nagase T, Ishikawa K, Miyajima N, et al. (1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.". DNA Res. 5 (1): 31-9. PMID 9628581.
Bunn RC, Jensen MA, Reed BC (1999). "Protein interactions with the glucose transporter binding protein GLUT1CBP that provide a link between GLUT1 and the cytoskeleton.". Mol. Biol. Cell 10 (4): 819-32. PMID 10198040.
Conforti L, Buckmaster EA, Tarlton A, et al. (1999). "The major brain isoform of kif1b lacks the putative mitochondria-binding domain.". Mamm. Genome 10 (6): 617-22. PMID 10341097.
Nagai M, Ichimiya S, Ozaki T, et al. (2000). "Identification of the full-length KIAA0591 gene encoding a novel kinesin-related protein which is mapped to the neuroblastoma suppressor gene locus at 1p36.2.". Int. J. Oncol. 16 (5): 907-16. PMID 10762626.
Nagase T, Kikuno R, Ishikawa K, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (2): 143-50. PMID 10819331.
Zhao C, Takita J, Tanaka Y, et al. (2001). "Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta.". Cell 105 (5): 587-97. PMID 11389829.
Yang HW, Chen YZ, Takita J, et al. (2001). "Genomic structure and mutational analysis of the human KIF1B gene which is homozygously deleted in neuroblastoma at chromosome 1p36.2.". Oncogene 20 (36): 5075-83. doi:10.1038/sj.onc.1204456. PMID 11526494.
Mok H, Shin H, Kim S, et al. (2002). "Association of the kinesin superfamily motor protein KIF1Balpha with postsynaptic density-95 (PSD-95), synapse-associated protein-97, and synaptic scaffolding molecule PSD-95/discs large/zona occludens-1 proteins.". J. Neurosci. 22 (13): 5253-8. doi:20026553. PMID 12097473.
Nakamura N, Miyake Y, Matsushita M, et al. (2003). "KIF1Bbeta2, capable of interacting with CHP, is localized to synaptic vesicles.". J. Biochem. 132 (3): 483-91. PMID 12204119.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Huang YS, Carson JH, Barbarese E, Richter JD (2003). "Facilitation of dendritic mRNA transport by CPEB.". Genes Dev. 17 (5): 638-53. doi:10.1101/gad.1053003. PMID 12629046.
Chen YY, Takita J, Chen YZ, et al. (2004). "Genomic structure and mutational analysis of the human KIF1Balpha gene located at 1p36.2 in neuroblastoma.". Int. J. Oncol. 23 (3): 737-44. PMID 12888911.
Rodriguez M, Yu X, Chen J, Songyang Z (2004). "Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains.". J. Biol. Chem. 278 (52): 52914-8. doi:10.1074/jbc.C300407200. PMID 14578343.
Nagaraja GM, Kandpal RP (2004). "Chromosome 13q12 encoded Rho GTPase activating protein suppresses growth of breast carcinoma cells, and yeast two-hybrid screen shows its interaction with several proteins.". Biochem. Biophys. Res. Commun. 313 (3): 654-65. PMID 14697242.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935.
Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.". Curr. Biol. 14 (16): 1436-50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.