KIF14

From Wikipedia, the free encyclopedia

Kinesin family member 14

Identifiers

KIF14; KIAA0042; MGC142302

External IDs

Gene ontology
Molecular Function:	• nucleotide binding • structural constituent of ribosome • microtubule motor activity • ATP binding
Cellular Component:	• intracellular • ribosome • microtubule • microtubule associated complex
Biological Process:	• translation • microtubule-based movement

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_014875 (mRNA)
NP_055690 (protein)

XM_619672 (mRNA)
XP_619672 (protein)

Location

Chr 1: 198.79 - 198.86 Mb

Chr 1: 138.28 - 138.34 Mb

Pubmed search

[1]

[2]

Kinesin family member 14, also known as KIF14, is a human gene.^[1]

[edit] References

^ Entrez Gene: KIF14 kinesin family member 14.

[edit] Further reading

Nomura N, Nagase T, Miyajima N, et al. (1995). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1.". DNA Res. 1 (5): 223–9. PMID 7584044.
Nakagawa T, Tanaka Y, Matsuoka E, et al. (1997). "Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.". Proc. Natl. Acad. Sci. U.S.A. 94 (18): 9654–9. PMID 9275178.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Corson TW, Huang A, Tsao MS, Gallie BL (2005). "KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers.". Oncogene 24 (30): 4741–53. doi:10.1038/sj.onc.1208641. PMID 15897902.
Gruneberg U, Neef R, Li X, et al. (2006). "KIF14 and citron kinase act together to promote efficient cytokinesis.". J. Cell Biol. 172 (3): 363–72. doi:10.1083/jcb.200511061. PMID 16431929.
Corson TW, Gallie BL (2006). "KIF14 mRNA expression is a predictor of grade and outcome in breast cancer.". Int. J. Cancer 119 (5): 1088–94. doi:10.1002/ijc.21954. PMID 16570270.
Carleton M, Mao M, Biery M, et al. (2006). "RNA interference-mediated silencing of mitotic kinesin KIF14 disrupts cell cycle progression and induces cytokinesis failure.". Mol. Cell. Biol. 26 (10): 3853–63. doi:10.1128/MCB.26.10.3853-3863.2006. PMID 16648480.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Bowles E, Corson TW, Bayani J, et al. (2007). "Profiling genomic copy number changes in retinoblastoma beyond loss of RB1.". Genes Chromosomes Cancer 46 (2): 118–29. doi:10.1002/gcc.20383. PMID 17099872.
Vasilescu J, Zweitzig DR, Denis NJ, et al. (2007). "The proteomic reactor facilitates the analysis of affinity-purified proteins by mass spectrometry: application for identifying ubiquitinated proteins in human cells.". J. Proteome Res. 6 (1): 298–305. doi:10.1021/pr060438j. PMID 17203973.
Corson TW, Zhu CQ, Lau SK, et al. (2007). "KIF14 messenger RNA expression is independently prognostic for outcome in lung cancer.". Clin. Cancer Res. 13 (11): 3229–34. doi:10.1158/1078-0432.CCR-07-0393. PMID 17545527.
Madhavan J, Coral K, Mallikarjuna K, et al. (2007). "High expression of KIF14 in retinoblastoma: association with older age at diagnosis.". Invest. Ophthalmol. Vis. Sci. 48 (11): 4901–6. doi:10.1167/iovs.07-0063. PMID 17962437.