Keratin 4

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keratin 4
Identifiers
Symbol KRT4
Alt. Symbols CYK4
Entrez 3851
HUGO 6441
OMIM 123940
RefSeq NM_002272
UniProt P19013
Other data
Locus Chr. 12 p12.2-q11

Keratin 4 is a type II cytokeratins. It is specifically found in differentiated layers of the mucosal and esophageal epithelia together with keratin 13. Mutations in the genes encoding this protein have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia.