KCNK17

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Potassium channel, subfamily K, member 17
Identifiers
Symbol(s) KCNK17; K2p17.1; TALK-2; TALK2; TASK-4; TASK4
External IDs OMIM: 607370 HomoloGene: 88928
Orthologs
Human Mouse
Entrez 89822 n/a
Ensembl ENSG00000124780 n/a
Uniprot Q96T54 n/a
Refseq NM_031460 (mRNA)
NP_113648 (protein)		 n/a (mRNA)
n/a (protein)
Location Chr 6: 39.37 - 39.39 Mb n/a
Pubmed search [1] n/a

Potassium channel, subfamily K, member 17, also known as KCNK17, is a human gene.[1]

This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This open channel, primarily expressed in the pancreas, is activated at alkaline pH.[1]

Contents

[edit] See also

[edit] References

  1. ^ a b Entrez Gene: KCNK17 potassium channel, subfamily K, member 17.

[edit] Further reading

  • Goldstein SA, Bayliss DA, Kim D, et al. (2006). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels.". Pharmacol. Rev. 57 (4): 527-40. doi:10.1124/pr.57.4.12. PMID 16382106. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711-8. doi:10.1101/gr.2435604. PMID 15342556. 
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805-11. doi:10.1038/nature02055. PMID 14574404. 
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Girard C, Duprat F, Terrenoire C, et al. (2001). "Genomic and functional characteristics of novel human pancreatic 2P domain K(+) channels.". Biochem. Biophys. Res. Commun. 282 (1): 249-56. doi:10.1006/bbrc.2001.4562. PMID 11263999. 
  • Decher N, Maier M, Dittrich W, et al. (2001). "Characterization of TASK-4, a novel member of the pH-sensitive, two-pore domain potassium channel family.". FEBS Lett. 492 (1-2): 84-9. PMID 11248242. 

[edit] External links

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v • d • e
Membrane transport protein: ion channels
Ca2+: Calcium channel
Na+: Sodium channel
Navα (1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.9, 7A) • Navβ (1, 2, 3, 4) • Epithelial sodium channel
K+: Potassium channel
Cl-: Chloride channel
Porin
Cations: TRP
TRPA (1) • TRPC (1, 2, 3, 4, 4AP, 5, 6, 7) • TRPM (1, 2, 3, 4, 5, 6, 7, 8) • TRPML (Mucolipin-1) • TRPP (1, 2) • TRPV (1, 2, 3, 4, 5, 6)
Other/general