Juglone 3-monooxygenase

From Wikipedia, the free encyclopedia

In enzymology, a juglone 3-monooxygenase (EC 1.14.99.27) is an enzyme that catalyzes the chemical reaction

5-hydroxy-1,4-naphthoquinone + AH₂ + O₂ 3,5-dihydroxy-1,4-naphthoquinone + A + H₂O

The 3 substrates of this enzyme are 5-hydroxy-1,4-naphthoquinone, AH2, and O₂, whereas its 3 products are 3,5-dihydroxy-1,4-naphthoquinone, A, and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is 5-hydroxy-1,4-naphthoquinone,hydrogen-donor:oxygen oxidoreductase (3-hydroxylating). Other names in common use include juglone hydroxylase, naphthoquinone hydroxylase, and naphthoquinone-hydroxylase.

[edit] References

• IUBMB entry for 1.14.99.27
• BRENDA references for 1.14.99.27 (Recommended.)
• PubMed references for 1.14.99.27
• PubMed Central references for 1.14.99.27
• Google Scholar references for 1.14.99.27
• Rettenmaier H, Lingens F (1985). "Purification and some properties of two isofunctional juglone hydroxylases from Pseudomonas putida J1". Biol. Chem. Hoppe. Seyler. 366: 637–46. PMID 4041238. 

[edit] External links

The CAS registry number for this enzyme class is 98865-54-4.

• IUBMB entry for 1.14.99.27

• KEGG entry for 1.14.99.27

• BRENDA entry for 1.14.99.27

• NiceZyme view of 1.14.99.27

• EC2PDB: PDB structures for 1.14.99.27

• PRIAM entry for 1.14.99.27

• PUMA2 entry for 1.14.99.27

• IntEnz: Integrated Enzyme entry for 1.14.99.27

• MetaCyc entry for 1.14.99.27

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050012: juglone 3-monooxygenase

• AMIGO entry for GO code 0050012: juglone 3-monooxygenase