JUB (gene)

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Jub, ajuba homolog (Xenopus laevis)
Identifiers
Symbol(s) JUB; Ajuba; MGC15563
External IDs OMIM: 609066 MGI: 1341886 HomoloGene: 7789
Orthologs
Human Mouse
Entrez 84962 16475
Ensembl ENSG00000129474 ENSMUSG00000022178
Refseq NM_032876 (mRNA)
NP_116265 (protein)		 NM_010590 (mRNA)
NP_034720 (protein)
Location Chr 14: 22.51 - 22.52 Mb Chr 14: 53.52 - 53.53 Mb
Pubmed search [1] [2]

Jub, ajuba homolog (Xenopus laevis), also known as JUB, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: JUB jub, ajuba homolog (Xenopus laevis).

[edit] Further reading

  • Goyal RK, Lin P, Kanungo J, et al. (1999). "Ajuba, a novel LIM protein, interacts with Grb2, augments mitogen-activated protein kinase activity in fibroblasts, and promotes meiotic maturation of Xenopus oocytes in a Grb2- and Ras-dependent manner.". Mol. Cell. Biol. 19 (6): 4379–89. PMID 10330178. 
  • Kanungo J, Pratt SJ, Marie H, Longmore GD (2000). "Ajuba, a cytosolic LIM protein, shuttles into the nucleus and affects embryonal cell proliferation and fate decisions.". Mol. Biol. Cell 11 (10): 3299–313. PMID 11029037. 
  • Marie H, Billups D, Bedford FK, et al. (2002). "The amino terminus of the glial glutamate transporter GLT-1 interacts with the LIM protein Ajuba.". Mol. Cell. Neurosci. 19 (2): 152–64. doi:10.1006/mcne.2001.1066. PMID 11860269. 
  • Marie H, Pratt SJ, Betson M, et al. (2003). "The LIM protein Ajuba is recruited to cadherin-dependent cell junctions through an association with alpha-catenin.". J. Biol. Chem. 278 (2): 1220–8. doi:10.1074/jbc.M205391200. PMID 12417594. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Hirota T, Kunitoku N, Sasayama T, et al. (2003). "Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells.". Cell 114 (5): 585–98. PMID 13678582. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Pratt SJ, Epple H, Ward M, et al. (2005). "The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration.". J. Cell Biol. 168 (5): 813–24. doi:10.1083/jcb.200406083. PMID 15728191. 
  • Benzinger A, Muster N, Koch HB, et al. (2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.". Mol. Cell Proteomics 4 (6): 785–95. doi:10.1074/mcp.M500021-MCP200. PMID 15778465. 
  • Kisseleva M, Feng Y, Ward M, et al. (2005). "The LIM protein Ajuba regulates phosphatidylinositol 4,5-bisphosphate levels in migrating cells through an interaction with and activation of PIPKI alpha.". Mol. Cell. Biol. 25 (10): 3956–66. doi:10.1128/MCB.25.10.3956-3966.2005. PMID 15870270. 
  • Feng Y, Longmore GD (2005). "The LIM protein Ajuba influences interleukin-1-induced NF-kappaB activation by affecting the assembly and activity of the protein kinase Czeta/p62/TRAF6 signaling complex.". Mol. Cell. Biol. 25 (10): 4010–22. doi:10.1128/MCB.25.10.4010-4022.2005. PMID 15870274. 
  • Abe Y, Ohsugi M, Haraguchi K, et al. (2006). "LATS2-Ajuba complex regulates gamma-tubulin recruitment to centrosomes and spindle organization during mitosis.". FEBS Lett. 580 (3): 782–8. doi:10.1016/j.febslet.2005.12.096. PMID 16413547. 
  • Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. 
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