User:JonSDSUGrad/Sandbox/Demo dTGFBI

From Wikipedia, the free encyclopedia


Transforming growth factor, beta-induced, 68kDa
PDB rendering based on 1x3b.
Available structures: 1x3b
Identifiers
Symbol(s) TGFBI; BIGH3; CDB1; CDG2; CDGG1; CSD; CSD1; CSD2; CSD3; EBMD; LCD1
External IDs OMIM: 601692 MGI99959 HomoloGene37294
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 7045 21810
Ensembl ENSG00000120708 ENSMUSG00000035493
Uniprot Q15582 Q19PV3
Refseq NM_000358 (mRNA)
NP_000349 (protein)
NM_009369 (mRNA)
NP_033395 (protein)
Location Chr 5: 135.39 - 135.43 Mb Chr 13: 56.62 - 56.65 Mb
Pubmed search [1] [2]

Transforming growth factor, beta-induced, 68kDa, also known as TGFBI, is a human gene.[1]


[edit] References

[edit] Further reading

  • Pieramici SF, Afshari NA (2006). "Genetics of corneal dystrophies: the evolving landscape.". Current opinion in ophthalmology 17 (4): 361-6. doi:10.1097/01.icu.0000233955.94347.84. PMID 16900028. 
  • Schmitt-Bernard CF, Pouliquen Y, Argilès A (2004). "[BIG-H3 protein: mutation of codon 124 and corneal amyloidosis]". Journal français d'ophtalmologie 27 (5): 510-22. PMID 15179309. 
  • Fujiki K, Nakayasu K, Kanai A (2001). "Corneal dystrophies in Japan.". J. Hum. Genet. 46 (8): 431-5. PMID 11501939. 
  • Becker J, Volland S, Noskova I, et al. (2008). "Keratoepithelin reverts the suppression of tissue factor pathway inhibitor 2 by MYCN in human neuroblastoma: a mechanism to inhibit invasion.". Int. J. Oncol. 32 (1): 235-40. PMID 18097563. 
  • Ahmed AA, Mills AD, Ibrahim AE, et al. (2008). "The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel.". Cancer Cell 12 (6): 514-27. doi:10.1016/j.ccr.2007.11.014. PMID 18068629. 
  • Takács L, Losonczy G, Matesz K, et al. (2007). "TGFBI (BIGH3) gene mutations in Hungary--report of the novel F547S mutation associated with polymorphic corneal amyloidosis.". Mol. Vis. 13: 1976-83. PMID 17982422. 
  • Kim JE, Han MS, Bae YC, et al. (2007). "Anterior segment dysgenesis after overexpression of transforming growth factor-beta-induced gene, beta igh3, in the mouse eye.". Mol. Vis. 13: 1942-52. PMID 17982418. 
  • Zhao XC, Nakamura H, Subramanyam S, et al. (2007). "Spontaneous and inheritable R555Q mutation in the TGFBI/BIGH3 gene in two unrelated families exhibiting Bowman's layer corneal dystrophy.". Ophthalmology 114 (11): e39-46. doi:10.1016/j.ophtha.2007.07.029. PMID 17980739. 
  • Yoo JH, Kim E, Kim J, Cho HS (2007). "Crystallization and preliminary crystallographic analysis of the fourth FAS1 domain of human BigH3.". Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 63 (Pt 10): 893-5. doi:10.1107/S1744309107039358. PMID 17909299. 
  • Correa-Gomez V, Villalvazo-Cordero L, Zenteno JC (2007). "The TGFBI A546D mutation causes an atypical type of lattice corneal dystrophy.". Mol. Vis. 13: 1695-700. PMID 17893671. 
  • Kobayashi A, Fujiki K, Fujimaki T, et al. (2007). "In vivo laser confocal microscopic findings of corneal stromal dystrophies.". Arch. Ophthalmol. 125 (9): 1168-73. doi:10.1001/archopht.125.9.1168. PMID 17846354. 
  • Tian X, Fujiki K, Zhang Y, et al. (2007). "A novel variant lattice corneal dystrophy caused by association of mutation (V625D) in TGFBI gene.". Am. J. Ophthalmol. 144 (3): 473-5. doi:10.1016/j.ajo.2007.04.015. PMID 17765440. 
  • Karring H, Valnickova Z, Thøgersen IB, et al. (2007). "Evidence against a blood derived origin for transforming growth factor beta induced protein in corneal disorders caused by mutations in the TGFBI gene.". Mol. Vis. 13: 997-1004. PMID 17653042. 
  • Baron C, Somogyi R, Greller LD, et al. (2007). "Prediction of graft-versus-host disease in humans by donor gene-expression profiling.". PLoS Med. 4 (1): e23. doi:10.1371/journal.pmed.0040023. PMID 17378698. 
  • Tang J, Zhou HW, Jiang JL, et al. (2007). "BetaIg-h3 is involved in the HAb18G/CD147-mediated metastasis process in human hepatoma cells.". Exp. Biol. Med. (Maywood) 232 (3): 344-52. PMID 17327467. 
  • Aldave AJ, Sonmez B, Forstot SL, et al. (2007). "A clinical and histopathologic examination of accelerated TGFBIp deposition after LASIK in combined granular-lattice corneal dystrophy.". Am. J. Ophthalmol. 143 (3): 416-9. doi:10.1016/j.ajo.2006.11.056. PMID 17317389. 
  • Atchaneeyasakul LO, Appukuttan B, Pingsuthiwong S, et al. (2006). "A novel H572R mutation in the transforming growth factor-beta-induced gene in a Thai family with lattice corneal dystrophy type I.". Jpn. J. Ophthalmol. 50 (5): 403-8. doi:10.1007/s10384-006-0357-6. PMID 17013691. 
  • Nam EJ, Sa KH, You DW, et al. (2006). "Up-regulated transforming growth factor beta-inducible gene h3 in rheumatoid arthritis mediates adhesion and migration of synoviocytes through alpha v beta3 integrin: Regulation by cytokines.". Arthritis Rheum. 54 (9): 2734-44. doi:10.1002/art.22076. PMID 16947382. 
  • Kim CD, Cho YJ, Park SH, et al. (2006). "Urinary transforming growth factor-beta-induced gene-h3 (betaig-h3) as a sensitive predictor in chronic cyclosporine nephrotoxicity.". Transplant. Proc. 38 (5): 1314-9. doi:10.1016/j.transproceed.2006.02.070. PMID 16797290.